Simultaneous determination of sulfonamides, tetracyclines and tiamulin in swine wastewater by solid-phase extraction and liquid chromatography-mass spectrometry

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境水质学国家重点实验室

	Simultaneous determination of sulfonamides, tetracyclines and tiamulin in swine wastewater by solid-phase extraction and liquid chromatography-mass spectrometry
	Ben, Weiwei; Qiang, Zhimin; Adams, Craig; Zhang, Heqing; Chen, Liping
刊名	JOURNAL OF CHROMATOGRAPHY A
	2008-08-22
卷号	1202 期号:2 页码:173-180
关键词	mass spectrometry antibiotics swine wastewater sulfonamide tetracycline macrolide
英文摘要	Little is known about the contamination level of antibiotics in swine wastewater in China. The highly complex matrix of swine wastewater, which generally has a chemical oxygen demand (COD) concentration as high as 15,000 mg/L, makes it difficult to detect antibiotics at trace levels. In this work, a highly selective and sensitive analytical method was developed for simultaneous determination of three classes of commonly used veterinary antibiotics including five sulfonamides, three tetracyclines and one macrolide in swine wastewater using solid-phase extraction (SPE) and liquid chromatography-mass spectrometry (LC-MS). The method detection limits (MDL) in the swine wastewater were determined to be between 5 and 91 ng/L, depending on specific antibiotics. Except sulfamethizole, all the other eight antibiotics were detected in the swine wastewaters collected from three concentrated swine feeding plants located in the Beijing (China) area, showing a concentration range of 0.62-32.67 mu g/L. These results reveal the representative concentration levels of selected antibiotics in the swine wastewaters of Beijing area. (C) 2008 Elsevier B.V. All rights reserved.
WOS记录号	WOS:000258696800009
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/22285]
专题	生态环境研究中心_环境水质学国家重点实验室
推荐引用方式 GB/T 7714	Ben, Weiwei,Qiang, Zhimin,Adams, Craig,et al. Simultaneous determination of sulfonamides, tetracyclines and tiamulin in swine wastewater by solid-phase extraction and liquid chromatography-mass spectrometry[J]. JOURNAL OF CHROMATOGRAPHY A,2008,1202(2):173-180.
APA	Ben, Weiwei,Qiang, Zhimin,Adams, Craig,Zhang, Heqing,&Chen, Liping.(2008).Simultaneous determination of sulfonamides, tetracyclines and tiamulin in swine wastewater by solid-phase extraction and liquid chromatography-mass spectrometry.JOURNAL OF CHROMATOGRAPHY A,1202(2),173-180.
MLA	Ben, Weiwei,et al."Simultaneous determination of sulfonamides, tetracyclines and tiamulin in swine wastewater by solid-phase extraction and liquid chromatography-mass spectrometry".JOURNAL OF CHROMATOGRAPHY A 1202.2(2008):173-180.