Hippo signaling in epithelial stem cells

	Hippo signaling in epithelial stem cells
	Yin, MX; Zhang, L
刊名	ACTA BIOCHIMICA ET BIOPHYSICA SINICA
	2015
卷号	47 期号:1 页码:39-45
关键词	Hippo YAP epithelial stem cells
通讯作者	Zhang, L (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, State Key Lab Cell Biol, Shanghai 200031, Peoples R China.,rayzhang@sibcb.ac.cn
英文摘要	Over the past decade, discoveries on Hippo signaling have revealed a complex signaling network integrating various signaling pathways to modulate tissue homeostasis, organ size control, tissue repair, and regeneration. Malfunction of the Hippo pathway is associated with tumor and cancer development. Moreover, Hippo signaling has been proposed to act in numerous stem cells in a variety of organisms. Recently, more attention has been paid to define the functions of the Hippo pathway in tissue-specific stem cells, which have great potential to be used in cell-based therapies. Here we provide an overview of its roles in regulating stem cells in epithelial tissues and its potential implications in related cancers.
学科主题	Biochemistry & Molecular Biology; Biophysics
类目[WOS]	Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]	TUMOR-SUPPRESSOR PATHWAY ; YES-ASSOCIATED PROTEIN ; ORGAN SIZE CONTROL ; AJUBA FAMILY PROTEINS ; TISSUE-GROWTH ; PROMOTES APOPTOSIS ; PROLIFERATION ARREST ; TEAD/TEF FAMILY ; YORKIE ACTIVITY ; ALPHA-CATENIN
收录类别	SCI
语种	英语
WOS记录号	WOS:000347411100006
内容类型	期刊论文
版本	出版稿
源URL	[http://202.127.25.143/handle/331003/12]
专题	上海生化细胞研究所_上海生科院生化细胞研究所
推荐引用方式 GB/T 7714	Yin, MX,Zhang, L. Hippo signaling in epithelial stem cells[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2015,47(1):39-45.
APA	Yin, MX,&Zhang, L.(2015).Hippo signaling in epithelial stem cells.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,47(1),39-45.
MLA	Yin, MX,et al."Hippo signaling in epithelial stem cells".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 47.1(2015):39-45.