Comparative effects of indole derivatives as antifouling agents on the growth of two marine diatom species

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物学与生物资源利用所重点实验室

	Comparative effects of indole derivatives as antifouling agents on the growth of two marine diatom species
	Yang, Cuiyun; Sun, Wenjun; Liu, Sujing; Xia, Chuanhai
刊名	CHEMISTRY AND ECOLOGY
	2015-05-19
卷号	31 期号:4 页码:299-307
关键词	indole derivatives EC50 diatom antifouling
ISSN号	0275-7540
通讯作者	Xia, CH (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Res Utilizat, Yantai 264003, Peoples R China. yangcy29@163.com
产权排序	[Yang, Cuiyun; Liu, Sujing; Xia, Chuanhai] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Res Utilizat, Yantai 264003, Peoples R China; [Sun, Wenjun] Yantai Univ, Food & Biol Engn Coll, Yantai 264005, Shandong, Peoples R China
英文摘要	Antifouling agents, used to prevent biofouling, need to be assessed for their impacts on marine organisms and environment before the application. Diatoms are one of the main components of fouling biofilms, which play important roles in the formation of biofouling. Particularly, diatoms are also the important ingredients of primary production and present interest as ecotoxicological models in marine environment. In this study, two benthic diatoms Nitzschia closterium f. minutissima and Navicula climacospheniae, widely distributed in fouling biofilm, were used as models for screening the activities of potential antifoulants. Nine indole derivatives were tested and CuSO4 was used as a reference. Indole derivatives showed significant anti-algal activities and the EC50 values of most indole derivatives were lower than that of CuSO4. Halogen substituent enhanced the anti-algal activities of compounds, and the most efficient compounds for N. closterium f. minutissima were gramine and 7-chloroindole with the EC50 values of 1.94 and 2.1 mg/L, while for N. climacospheniae, 7-chloroindole and 6-bromoindole were the most efficient and the EC50 values were 3.91 and 4.25 mg/L, respectively. In conclusion, indole derivatives would be one of the promising candidates as antifoulants and our results strengthened the need to perform antifouling activity assays and environment-friendly evaluations.
学科主题	Biochemistry & Molecular Biology ; Ecology ; Environmental Sciences
研究领域[WOS]	Natural Science Foundation [41206154] ; Yantai Science and Technology Development Project [2011063]
关键词[WOS]	ANTIBACTERIAL COMPOUNDS ; SYNTHETIC ANALOGS ; NATURAL-PRODUCTS ; ENVIRONMENT ; SETTLEMENT ; TOXICITY ; TRIBUTYLTIN ; METABOLITES ; COATINGS ; BACTERIA
收录类别	SCI
语种	英语
WOS记录号	WOS:000354372400001
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/8502]
专题	烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
推荐引用方式 GB/T 7714	Yang, Cuiyun,Sun, Wenjun,Liu, Sujing,et al. Comparative effects of indole derivatives as antifouling agents on the growth of two marine diatom species[J]. CHEMISTRY AND ECOLOGY,2015,31(4):299-307.
APA	Yang, Cuiyun,Sun, Wenjun,Liu, Sujing,&Xia, Chuanhai.(2015).Comparative effects of indole derivatives as antifouling agents on the growth of two marine diatom species.CHEMISTRY AND ECOLOGY,31(4),299-307.
MLA	Yang, Cuiyun,et al."Comparative effects of indole derivatives as antifouling agents on the growth of two marine diatom species".CHEMISTRY AND ECOLOGY 31.4(2015):299-307.