Impact of Magnesium(II) on Beryllium Fluorides in Solutions Studied by F-19 NMR Spectroscopy

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	Impact of Magnesium(II) on Beryllium Fluorides in Solutions Studied by F-19 NMR Spectroscopy
	Liu, Yixiang 1,3; Mao, Xian 2; Liu, Maili 1; Jiang, Ling 1
刊名	CHINESE JOURNAL OF CHEMISTRY
	2014-09-01
卷号	32 期号:9 页码:878-882
关键词	beryllium fluorides magnesium(II) F-19 NMR ion pair protein phosphorylation
英文摘要	Beryllium fluorides are widely used in protein phosphorylation studies to get stable transition state analogs or near attack conformers, which has attracted much attention. BeF3- is one of the optimal phosphoryl (PO3-) analogs for its identical geometry and charge, and Mg2+ naturally participates in the phosphoryl binding in biological systems. In solutions, BeF3- coexists with other beryllium fluorides (BeF42-, BeF2 and BeF+) and magnesium fluorides, and there are equilibriums between these species. In this article, F-19 NMR spectroscopy was applied to the investigation of the impact of magnesium(II) on beryllium fluorides. It has been found that when Mg2+ was introduced into the solutions, the chemical shifts, the intensities and the line widths of F-19 signals of various beryllium fluoride complexes were changed. After ionic strength correction, these effects were remarkable only for BeF42- and BeF3-, especially BeF42-, when the concentration of the fluoride ion is relatively low. Mechanism of the effects is proposed which involves ion pair formation between Mg2+ and beryllium fluorides.
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Multidisciplinary
研究领域[WOS]	Chemistry
关键词[WOS]	FLUOROBERYLLATE COMPLEXES ; CONSTANTS ; PHOSPHORYLATION ; ASPARTATE ; PROTEINS ; ALUMINUM ; CALCIUM ; DOMAIN ; ANALOG
收录类别	SCI
语种	英语
WOS记录号	WOS:000342279500008
公开日期	2015-07-14
内容类型	期刊论文
源URL	[http://ir.wipm.ac.cn/handle/112942/1439]
专题	武汉物理与数学研究所_磁共振基础研究部
作者单位	1.Chinese Acad Sci, Key Lab Magnet Resonance Biol Syst, Wuhan Ctr Magnet Resonance,Wuhan Inst Phys & Math, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan 430071, Hubei, Peoples R China 2.Case Western Reserve Univ, Dept Pharmacol, Sch Med, Cleveland, OH 44106 USA 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Liu, Yixiang,Mao, Xian,Liu, Maili,et al. Impact of Magnesium(II) on Beryllium Fluorides in Solutions Studied by F-19 NMR Spectroscopy[J]. CHINESE JOURNAL OF CHEMISTRY,2014,32(9):878-882.
APA	Liu, Yixiang,Mao, Xian,Liu, Maili,&Jiang, Ling.(2014).Impact of Magnesium(II) on Beryllium Fluorides in Solutions Studied by F-19 NMR Spectroscopy.CHINESE JOURNAL OF CHEMISTRY,32(9),878-882.
MLA	Liu, Yixiang,et al."Impact of Magnesium(II) on Beryllium Fluorides in Solutions Studied by F-19 NMR Spectroscopy".CHINESE JOURNAL OF CHEMISTRY 32.9(2014):878-882.