An upper limit for macromolecular crowding effects

CORC > 武汉物理与数学研究所 > 中国科学院武汉物理与数学研究所 > 2011年以前论文发表（包括2011年）

	An upper limit for macromolecular crowding effects
	Miklos, Andrew C.1; Li, Conggang 1,2; Sorrell, Courtney D.3,4,5,6; Lyon, L. Andrew 3,4; Pielak, Gary J.1,7
刊名	BMC BIOPHYSICS
	2011-05-31
卷号	4 期号:1 页码:13-13
产权排序	第二
英文摘要	Background: Solutions containing high macromolecule concentrations are predicted to affect a number of protein properties compared to those properties in dilute solution. In cells, these macromolecular crowders have a large range of sizes and can occupy 30% or more of the available volume. We chose to study the stability and ps-ns internal dynamics of a globular protein whose radius is similar to 2 nm when crowded by a synthetic microgel composed of poly(N-isopropylacrylamide-co-acrylic acid) with particle radii of similar to 300 nm.
学科主题	波谱学
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Biophysics
研究领域[WOS]	Biophysics
关键词[WOS]	MICROGEL THIN-FILMS ; HYDROGEN-EXCHANGE ; PROTEIN STABILITY ; CHYMOTRYPSIN INHIBITOR ; BACKBONE DYNAMICS ; NMR RELAXATION ; MECHANISM ; RATES
收录类别	SCI
语种	英语
WOS记录号	WOS:000299411300001
内容类型	期刊论文
源URL	[http://ir.wipm.ac.cn/handle/112942/1933]
专题	武汉物理与数学研究所_2011年以前论文发表（包括2011年）
作者单位	1.Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA 2.Chinese Acad Sci, Wuhan Inst Phys & Math, State Key Lab Magnet Resonance Mol & Atom Phys, Wuhan 430071, Peoples R China 3.Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA 4.Georgia Inst Technol, Petit Inst Bioengn & Biosci, Atlanta, GA 30332 USA 5.Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada 6.Univ N Carolina, Dept Biochem & Biophys, Chapel Hill, NC 27599 USA 7.Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA
推荐引用方式 GB/T 7714	Miklos, Andrew C.,Li, Conggang,Sorrell, Courtney D.,et al. An upper limit for macromolecular crowding effects[J]. BMC BIOPHYSICS,2011,4(1):13-13.
APA	Miklos, Andrew C.,Li, Conggang,Sorrell, Courtney D.,Lyon, L. Andrew,&Pielak, Gary J..(2011).An upper limit for macromolecular crowding effects.BMC BIOPHYSICS,4(1),13-13.
MLA	Miklos, Andrew C.,et al."An upper limit for macromolecular crowding effects".BMC BIOPHYSICS 4.1(2011):13-13.