ADHDgene: a genetic database for attention deficit hyperactivity disorder

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	ADHDgene: a genetic database for attention deficit hyperactivity disorder
	Zhang, Liuyan1,2 ; Chang, Suhua1,2 ; Li, Zhao1,2 ; Zhang, Kunlin1 ; Du, Yang 1,2; Ott, Jurg 1; Wang, Jing1
刊名	NUCLEIC ACIDS RESEARCH
	2012
卷号	40 期号:D1 页码:D1003-D1009
ISSN号	0305-1048
通讯作者	Wang, J (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
产权排序	1
英文摘要	With a worldwide prevalence of similar to 5%, attention deficit hyperactivity disorder (ADHD) has become one of the most common psychiatric disorders. The polygenetic nature of ADHD indicates that multiple genes jointly contribute to the development of this complex disease. Studies aiming to explore genetic susceptibility of ADHD have been increasing in recent years. There is a growing need to integrate the genetic data from various genetic studies to provide a comprehensive data set and uniform access for convenience of in-depth data mining. So far, there has been no such effort for ADHD. To address the genetic complexity of ADHD, we developed the ADHDgene database by integrating ADHD-related genetic factors by profound literature reading. Based on the data from the literature, extended functional analysis, including linkage disequilibrium analysis, pathway-based analysis and gene mapping were performed to provide new insights into genetic causes of ADHD. Moreover, powerful search tools and a graphical browser were developed to facilitate the navigation of the data and data connections. As the first genetic database for ADHD, ADHDgene aims to provide researchers with a central genetic resource and analysis platform for ADHD and is freely available at http://adhd.psych.ac.cn/.
学科主题	Developmental psychology， Medical psychology
收录类别	SCI
项目简介	Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-EW-J-8); National Natural Science Foundation of China (81101545). Funding for open access charge: Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-EW-J-8). The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors.
原文出处	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245028/pdf/gkr992.pdf
语种	英语
WOS记录号	WOS:000298601300150
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/10865]
专题	心理研究所_中国科学院心理健康重点实验室
作者单位	1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Liuyan,Chang, Suhua,Li, Zhao,et al. ADHDgene: a genetic database for attention deficit hyperactivity disorder[J]. NUCLEIC ACIDS RESEARCH,2012,40(D1):D1003-D1009.
APA	Zhang, Liuyan.,Chang, Suhua.,Li, Zhao.,Zhang, Kunlin.,Du, Yang.,...&Wang, Jing.(2012).ADHDgene: a genetic database for attention deficit hyperactivity disorder.NUCLEIC ACIDS RESEARCH,40(D1),D1003-D1009.
MLA	Zhang, Liuyan,et al."ADHDgene: a genetic database for attention deficit hyperactivity disorder".NUCLEIC ACIDS RESEARCH 40.D1(2012):D1003-D1009.