Studying the mechanism of CD47-SIRP alpha interactions on red blood cells by single molecule force spectroscopy

	Studying the mechanism of CD47-SIRP alpha interactions on red blood cells by single molecule force spectroscopy
	Pan, Yangang ; Wang, Feng ; Liu, Yanhou ; Jiang,Junguang ; Yang,Yong-Guang ; Wang,Hongda
刊名	nanoscale
	2014
卷号	6 期号:17 页码:9951-9954
关键词	INTEGRIN-ASSOCIATED PROTEIN CD47 EXPRESSION RECOGNITION BINDING MICROSCOPY STORAGE FAMILY
ISSN号	2040-3364
通讯作者	yang,yg
中文摘要	the interaction forces and binding kinetics between sirpa and cd47 were investigated by single-molecule force spectroscopy (smfs) on both fresh and experimentally aged human red blood cells (hrbcs). we found that cd47 experienced a conformation change after oxidation, which influenced the interaction force and the position of the energy barrier between sirpa and cd47. our results are significant for understanding the mechanism of phagocytosis of red blood cells at the single molecule level.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000340520500007
公开日期	2015-03-27
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/50714]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Pan, Yangang,Wang, Feng,Liu, Yanhou,et al. Studying the mechanism of CD47-SIRP alpha interactions on red blood cells by single molecule force spectroscopy[J]. nanoscale,2014,6(17):9951-9954.
APA	Pan, Yangang,Wang, Feng,Liu, Yanhou,Jiang,Junguang,Yang,Yong-Guang,&Wang,Hongda.(2014).Studying the mechanism of CD47-SIRP alpha interactions on red blood cells by single molecule force spectroscopy.nanoscale,6(17),9951-9954.
MLA	Pan, Yangang,et al."Studying the mechanism of CD47-SIRP alpha interactions on red blood cells by single molecule force spectroscopy".nanoscale 6.17(2014):9951-9954.