Two Unusual Rearranged Flavan Derivatives from Narcissus tazetta var. chinensis

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	Two Unusual Rearranged Flavan Derivatives from Narcissus tazetta var. chinensis
	[Fu, Ka-Li ; Shen, Yun-Heng ; Lu, Lu ; Li, Bo ; Yang, Xian-Wen ; Su, Juan ; Liu, Run-Hui ; Zhang, Wei-Dong] Second Mil Med Univ, Sch Pharm, Dept Phytochem, Shanghai 200433, Peoples R China ; [Zhang, Wei-Dong] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200030, Peoples R China ; [Li, Bo] China State Inst Pharmaceut Ind, Shanghai Inst Pharmaceut Ind, Shanghai 200040, Peoples R China ; [Yang, Xian-Wen] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China
刊名	HELVETICA CHIMICA ACTA
	2013
卷号	96 期号:2 页码:338-344
ISSN号	0018-019X
通讯作者	shenyunheng9217018@yahoo.com.cn ; wdzhangy@hotmail.com
中文摘要	Two unusual rearranged flavan derivatives with a rare bicyclo[3.3.1]non-3-ene-2,9-dione ring, tazettone A (1) and tazettone B (2), together with five known flavans, 3-7, were isolated from the bulbs of Narcissus tazetta var. chinensis Roem. The structures of two new compounds were elucidated by spectroscopic analyses, including 1D- and 2D-NMR spectroscopy. All of the isolated compounds were evaluated for their cytotoxicities against four human tumor cell lines A549, HCT116, SK-BR-3, and HepG2. Compounds 1 and 2 were almost inactive against all tested cell lines, while compounds 3-7 exhibited moderate or weak cytotoxicities against the tested cell lines.
学科主题	Chemistry, Multidisciplinary
资助信息	The work was supported by program NCET Foundation, NSFC (30725045), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCMCANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300), and the Scientific Foundation of Shanghai, P. R. China (09DZ1975700, 09DZ1971500,10DZ1971700, 11DZ1970601, 11DZ1970602). The Twelfth Five-Year National Science & Technology Support Program (Number: 2012BAI29B06).
原文出处	WILEY-V C H VERLAG GMBH
语种	英语
WOS记录号	WOS:000316274600019
公开日期	2015-01-22
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/11070]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
推荐引用方式 GB/T 7714	[Fu, Ka-Li,Shen, Yun-Heng,Lu, Lu,et al. Two Unusual Rearranged Flavan Derivatives from Narcissus tazetta var. chinensis[J]. HELVETICA CHIMICA ACTA,2013,96(2):338-344.
APA	[Fu, Ka-Li.,Shen, Yun-Heng.,Lu, Lu.,Li, Bo.,Yang, Xian-Wen.,...&[Yang, Xian-Wen] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China.(2013).Two Unusual Rearranged Flavan Derivatives from Narcissus tazetta var. chinensis.HELVETICA CHIMICA ACTA,96(2),338-344.
MLA	[Fu, Ka-Li,et al."Two Unusual Rearranged Flavan Derivatives from Narcissus tazetta var. chinensis".HELVETICA CHIMICA ACTA 96.2(2013):338-344.