Effective Surface Charge Density Determines the Electrostatic Attraction between Nanoparticles and Cells

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	Effective Surface Charge Density Determines the Electrostatic Attraction between Nanoparticles and Cells
	Su, Gaoxing ; Zhou, Hongyu ; Mu, Qingxin ; Zhang, Yi ; Li, Liwen ; Jiao, Peifu ; Jiang, Guibin ; Yan, Bing
刊名	Chemistry; Science & Technology - Other Topics; Materials Science
	2012
卷号	116 期号:8 页码:4993-4998
ISSN号	1932-7447
中文摘要	We examine the origin of the electrostatic attraction between nanoparticle (NP) and cells by synthesizing a NP array with a continuous change in surface charge density (SCD). This attraction does not show a linear and continuous change, but a sharp increase as the positive SCD increases. The results of zeta potential measurements of the naked and protein bound NPs reveal that excessive charges on surface ligands are partially shielded, and the noncovalent protein bindings do not influence NP cell electrostatic interactions. The effective SCD on the outmost layer of NPs determined the electrostatic attraction between NPs and cells
WOS记录号	WOS:000300911600008
公开日期	2014-11-27
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/8048]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Su, Gaoxing,Zhou, Hongyu,Mu, Qingxin,et al. Effective Surface Charge Density Determines the Electrostatic Attraction between Nanoparticles and Cells[J]. Chemistry; Science & Technology - Other Topics; Materials Science,2012,116(8):4993-4998.
APA	Su, Gaoxing.,Zhou, Hongyu.,Mu, Qingxin.,Zhang, Yi.,Li, Liwen.,...&Yan, Bing.(2012).Effective Surface Charge Density Determines the Electrostatic Attraction between Nanoparticles and Cells.Chemistry; Science & Technology - Other Topics; Materials Science,116(8),4993-4998.
MLA	Su, Gaoxing,et al."Effective Surface Charge Density Determines the Electrostatic Attraction between Nanoparticles and Cells".Chemistry; Science & Technology - Other Topics; Materials Science 116.8(2012):4993-4998.