Effect of nigranoic acid on Ca2+ influx and its downstream signal mechanism in NGF-differentiated PC12 cells
Yuan, Xiao-Xi1,2; Yang, Li-Ping1,2,3; Yang, Zhong-Lin1,2; Xiao, Wei-Lie1; Sun, Han-Dong1; Wu, Gui-Sheng1; Luo, Huai-Rong1
刊名JOURNAL OF ETHNOPHARMACOLOGY
2014-05-14
卷号153期号:3页码:725-731
关键词Nigranoic acid Ca2+ Schisandra sphaerandra BDNF c-fos NO
ISSN号0378-8741
通讯作者Xiao,WL (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China. ; xwl@mail.kib.ac.cn ; luohuairong@mail.kib.ac.cn
英文摘要Ethnopharmacological relevance: Schisandra chinensis has a long history of use as a famous traditional Chinese medicine. The plants of genus Schisandra, especially Schisandra neglecta, Schisandra rubriflora, and Schisandra sphaerandra are used in the same way as Schisandra chinensis in the folk medicine to treat insomnia, fatigue, increasing intelligence, and tranquilizing. Many studies showed that lignans were the major active components of Schisandra genus, whereas the bioactivity of abundant triterpenoids in Schisandra genus, such as nigranoic acid (SBB1, 3,4-secocycloartene triterpenoid), has not been examined yet in neuropathology.
类目[WOS]Plant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine
关键词[WOS]LONG-TERM POTENTIATION ; INDUCED MEMORY IMPAIRMENT ; NERVE GROWTH-FACTOR ; SCHISANDRA-CHINENSIS ; NITRIC-OXIDE ; GENE-EXPRESSION ; MICE ; BDNF ; ACTIVATION ; RECEPTORS
收录类别SCI
资助信息Yunnan provincial government [20080A007, 2012FB178];100 Talents Program of the Chinese Academy of Sciences [2009312D11022];National Natural Science Foundation of China [81373290]
语种英语
WOS记录号WOS:000337648800021
公开日期2014-07-28
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/18200]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
3.Yunnan Inst Tradit Chinese Med & Mat Med, Kunming 650223, Yunnan, Peoples R China
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GB/T 7714
Yuan, Xiao-Xi,Yang, Li-Ping,Yang, Zhong-Lin,et al. Effect of nigranoic acid on Ca2+ influx and its downstream signal mechanism in NGF-differentiated PC12 cells[J]. JOURNAL OF ETHNOPHARMACOLOGY,2014,153(3):725-731.
APA Yuan, Xiao-Xi.,Yang, Li-Ping.,Yang, Zhong-Lin.,Xiao, Wei-Lie.,Sun, Han-Dong.,...&Luo, Huai-Rong.(2014).Effect of nigranoic acid on Ca2+ influx and its downstream signal mechanism in NGF-differentiated PC12 cells.JOURNAL OF ETHNOPHARMACOLOGY,153(3),725-731.
MLA Yuan, Xiao-Xi,et al."Effect of nigranoic acid on Ca2+ influx and its downstream signal mechanism in NGF-differentiated PC12 cells".JOURNAL OF ETHNOPHARMACOLOGY 153.3(2014):725-731.
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