Synthesis and neurite outgrowth promoting activity of vibsanin B derivatives | |
Shao, Li-Dong1,2; Xu, Jun1,2; Gao, Xiu1,2; He, Juan1; Zhao, Yu1; Peng, Li-Yan1; Luo, Huai-Rong1; Xia, Chengfeng1; Zhao, Qin-Shi1 | |
刊名 | TETRAHEDRON LETTERS |
2014-06-04 | |
卷号 | 55期号:23页码:3414-3417 |
关键词 | Intramolecular hetero-DA reaction Retro-aldol like ring opening reaction Vibsanin B Neurite outgrowth promoting |
ISSN号 | 0040-4039 |
通讯作者 | Xia,CF (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China. ; xiachengfeng@mail.kib.ac.cn ; ginshizhao@mail.kib.ac.cn |
英文摘要 | Intramolecular hetero-DA reaction and unexpected retro-aldol like ring opening reaction were performed. As a result, six derivatives with different skeletons of vibsane-type diterpenoids were synthesized from vibsanin B within three steps. Moreover, compounds 2, 3, and 6 enhanced the neurite outgrowth of NGF-mediated PC12 cells. (C) 2014 Elsevier Ltd. All rights reserved. |
学科主题 | Chemistry, Organic |
类目[WOS] | Chemistry, Organic |
研究领域[WOS] | Chemistry |
关键词[WOS] | VIBURNUM-AWABUKI ; DITERPENES ; ODORATISSIMUM ; TRITERPENOIDS ; CYLINDRICUM |
收录类别 | SCI ; IC |
资助信息 | National Natural Science Foundation [81102347, U0932602, 90813004, 21272242];Yunnan High-End Technology Professionals Introduction Program [2010CI117];National Basic Research Program (973 Program) of China [2011CB915503] |
语种 | 英语 |
WOS记录号 | WOS:000337206500005 |
公开日期 | 2014-07-28 |
内容类型 | 期刊论文 |
源URL | [http://ir.kib.ac.cn/handle/151853/18194] |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 10049, Peoples R China |
推荐引用方式 GB/T 7714 | Shao, Li-Dong,Xu, Jun,Gao, Xiu,et al. Synthesis and neurite outgrowth promoting activity of vibsanin B derivatives[J]. TETRAHEDRON LETTERS,2014,55(23):3414-3417. |
APA | Shao, Li-Dong.,Xu, Jun.,Gao, Xiu.,He, Juan.,Zhao, Yu.,...&Zhao, Qin-Shi.(2014).Synthesis and neurite outgrowth promoting activity of vibsanin B derivatives.TETRAHEDRON LETTERS,55(23),3414-3417. |
MLA | Shao, Li-Dong,et al."Synthesis and neurite outgrowth promoting activity of vibsanin B derivatives".TETRAHEDRON LETTERS 55.23(2014):3414-3417. |
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