Synthesis and neurite outgrowth promoting activity of vibsanin B derivatives
Shao, Li-Dong1,2; Xu, Jun1,2; Gao, Xiu1,2; He, Juan1; Zhao, Yu1; Peng, Li-Yan1; Luo, Huai-Rong1; Xia, Chengfeng1; Zhao, Qin-Shi1
刊名TETRAHEDRON LETTERS
2014-06-04
卷号55期号:23页码:3414-3417
关键词Intramolecular hetero-DA reaction Retro-aldol like ring opening reaction Vibsanin B Neurite outgrowth promoting
ISSN号0040-4039
通讯作者Xia,CF (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China. ; xiachengfeng@mail.kib.ac.cn ; ginshizhao@mail.kib.ac.cn
英文摘要Intramolecular hetero-DA reaction and unexpected retro-aldol like ring opening reaction were performed. As a result, six derivatives with different skeletons of vibsane-type diterpenoids were synthesized from vibsanin B within three steps. Moreover, compounds 2, 3, and 6 enhanced the neurite outgrowth of NGF-mediated PC12 cells. (C) 2014 Elsevier Ltd. All rights reserved.
学科主题Chemistry, Organic
类目[WOS]Chemistry, Organic
研究领域[WOS]Chemistry
关键词[WOS]VIBURNUM-AWABUKI ; DITERPENES ; ODORATISSIMUM ; TRITERPENOIDS ; CYLINDRICUM
收录类别SCI ; IC
资助信息National Natural Science Foundation [81102347, U0932602, 90813004, 21272242];Yunnan High-End Technology Professionals Introduction Program [2010CI117];National Basic Research Program (973 Program) of China [2011CB915503]
语种英语
WOS记录号WOS:000337206500005
公开日期2014-07-28
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/18194]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Univ Chinese Acad Sci, Beijing 10049, Peoples R China
推荐引用方式
GB/T 7714
Shao, Li-Dong,Xu, Jun,Gao, Xiu,et al. Synthesis and neurite outgrowth promoting activity of vibsanin B derivatives[J]. TETRAHEDRON LETTERS,2014,55(23):3414-3417.
APA Shao, Li-Dong.,Xu, Jun.,Gao, Xiu.,He, Juan.,Zhao, Yu.,...&Zhao, Qin-Shi.(2014).Synthesis and neurite outgrowth promoting activity of vibsanin B derivatives.TETRAHEDRON LETTERS,55(23),3414-3417.
MLA Shao, Li-Dong,et al."Synthesis and neurite outgrowth promoting activity of vibsanin B derivatives".TETRAHEDRON LETTERS 55.23(2014):3414-3417.
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