Chiral model complexes for methane monooxygenase and their asymmetric catalysis of styrene epoxidation

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	Chiral model complexes for methane monooxygenase and their asymmetric catalysis of styrene epoxidation
	Wei JF(魏俊发) ; Yu XD(俞贤达) ; Jin DS(金道森)
刊名	中国科学B辑(英文版)
	1998
卷号	41 期号:3 页码:247-254
关键词	methane monooxygenase dinuclear complex mimick enzyme epoxidation asymmetric catalysis biomimetic catalysis
ISSN号	1674-7291
中文摘要	Four chiral μ-phenolato dinuclear (VO)₂, Cr₂, Mn₂, and Fe₂ complexes with a phenolic ligand bearing two L-phenylanalines as complexing arms have been synthesized and characterized. Asymmetric epoxidations of styrene with these complexes as chiral models of methane monooxygenase (MMO) and iodosylbenzene as an oxygen atmo donor have been studied. The results reveal that the Mn₂ complex catalyzes asymmetric epoxidations of styrene with the formation of R-(+)-styrene oxide in 42.8% e.e. Contrarily, the (VO)₂ analogue complex gives S-(-)-styrene oxide in 19.2% e.e. EPR investigations suggest that the catalyzed epoxidations with the Mn₂, Cr₂ and Fe₂ complexes proceed via high-valent oxometal intermediates;while in the case of the (VO)₂ complex as catalyst, the epoxidation proceeds by a pathway that involves a complex of metal-iodine ligand. The catalytic activities of the complexes decreaes in a sequence of Mn₂>Cr₂>(VO)₂>Fe₂.
学科主题	物理化学
语种	英语
WOS记录号	WOS:000074448300003
公开日期	2014-05-23
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/5709]
专题	兰州化学物理研究所_非现建制
推荐引用方式 GB/T 7714	Wei JF,Yu XD,Jin DS. Chiral model complexes for methane monooxygenase and their asymmetric catalysis of styrene epoxidation[J]. 中国科学B辑(英文版),1998,41(3):247-254.
APA	Wei JF,Yu XD,&Jin DS.(1998).Chiral model complexes for methane monooxygenase and their asymmetric catalysis of styrene epoxidation.中国科学B辑(英文版),41(3),247-254.
MLA	Wei JF,et al."Chiral model complexes for methane monooxygenase and their asymmetric catalysis of styrene epoxidation".中国科学B辑(英文版) 41.3(1998):247-254.