Screening DNA Binders from Isoflavone Extracts of Red Clover by Centrifugal Ultrafiltration-LC-MSn

	Screening DNA Binders from Isoflavone Extracts of Red Clover by Centrifugal Ultrafiltration-LC-MSn
	Ma L ; Wang ZF ; Chen LN ; Song FR ; Liu ZQ ; Liu SY
刊名	chemical journal of chinese universities-chinese
	2013
卷号	34 期号:2 页码:331-335
关键词	LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY IONIZATION MASS-SPECTROMETRY TRIFOLIUM-PRATENSE TARGETING DNA SPECTROSCOPY FLAVONOIDS MECHANISM SURVIVIN BINDING
ISSN号	0251-0790
通讯作者	liu zq
中文摘要	centrifugal ultrafiltration and lc-ms methods were combined to screen dna-binding agents from traditional chinese medicine red clover isoflavone extracts. the results show that 10 red clover isoflavones have different binding degrees with dna. the sample was analyzed by lc-msn for identifying structures. among these flavones studied, the strongest five potential dna-binding agents are irilone-4(i)-o-beta-d-glucoside, glycitin, pratensein, irilone and biochanin a, respectively. a rapid centrifugal ultrafiltration-lc-ms platform for screening and identification of dna binders from the herbal extract and other complex system was established.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000317085400013
公开日期	2014-04-20
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/50494]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Ma L,Wang ZF,Chen LN,et al. Screening DNA Binders from Isoflavone Extracts of Red Clover by Centrifugal Ultrafiltration-LC-MSn[J]. chemical journal of chinese universities-chinese,2013,34(2):331-335.
APA	Ma L,Wang ZF,Chen LN,Song FR,Liu ZQ,&Liu SY.(2013).Screening DNA Binders from Isoflavone Extracts of Red Clover by Centrifugal Ultrafiltration-LC-MSn.chemical journal of chinese universities-chinese,34(2),331-335.
MLA	Ma L,et al."Screening DNA Binders from Isoflavone Extracts of Red Clover by Centrifugal Ultrafiltration-LC-MSn".chemical journal of chinese universities-chinese 34.2(2013):331-335.