A new approach to light up DNA/Ag nanocluster-based beacons for bioanalysis

	A new approach to light up DNA/Ag nanocluster-based beacons for bioanalysis
	Zhang LB ; Zhu JB ; Zhou ZX ; Guo SJ ; Li J ; Dong SJ ; Wang EK
刊名	chemical science
	2013
卷号	4 期号:10 页码:4004-4010
关键词	SILVER NANOCLUSTERS MOLECULAR BEACON LOGIC-CIRCUITS QUANTUM DOTS LABEL-FREE PROBE SUBSTRATE CLUSTERS MACHINE DEVICES
ISSN号	2041-6520
通讯作者	dong sj
中文摘要	dynamic dna assembly, operated in an autonomous and reconfigurable manner by controlling the kinetics of strand displacement reactions (sdr), is an ideal approach to amplify the fluorescent signals for molecular diagnostic and imaging. herein, we for the first time have demonstrated an enhancement of fluorescence intensity of dna/ag nanocluster-based beacons by the modulation of sdr. this is a new dna/ag ncs fluorescence light-up system through the use of the enhancer of g-rich overhang. such a sensing system can be used to develop a dna/ag nanocluster-based beacon for the fluorescent detection of nucleic acid and thrombin with high selectivity and sensitivity, in which the detection sensitivity could be further enhanced through additional exo iii based amplification.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000323843500029
公开日期	2014-04-16
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/50197]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Zhang LB,Zhu JB,Zhou ZX,et al. A new approach to light up DNA/Ag nanocluster-based beacons for bioanalysis[J]. chemical science,2013,4(10):4004-4010.
APA	Zhang LB.,Zhu JB.,Zhou ZX.,Guo SJ.,Li J.,...&Wang EK.(2013).A new approach to light up DNA/Ag nanocluster-based beacons for bioanalysis.chemical science,4(10),4004-4010.
MLA	Zhang LB,et al."A new approach to light up DNA/Ag nanocluster-based beacons for bioanalysis".chemical science 4.10(2013):4004-4010.