Kadpolysperins A-N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma | |
Dong, Ke1,2; Pu, Jian-Xin1; Du, Xue1; Su, Jia1; Li, Xiao-Nian1; Yang, Jian-Hong1; Zhao, Wei3; Li, Yan1; Sun, Han-Dong1 | |
刊名 | TETRAHEDRON |
2012-06-17 | |
卷号 | 68期号:24页码:4820-4829 |
关键词 | Kadsura polysperma Lanostane triterpene acid Kadpolysperins Cytotoxicity |
ISSN号 | 0040-4020 |
通讯作者 | Pu, JX (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China,pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn |
英文摘要 | Fourteen new lanostane triterpene acids (1-14), and five known analogues (15-19) were isolated from the stems of Kadsura polysperma. Compound 1, with a rearranged tetracyclic skeleton, is an important biogenic precursor of longipedlactone skeleton. Compounds 2-6 are members of 18(13 -> 12)-abeo-lanostane triterpene acids. The structures of new compounds were elucidated by spectroscopic evidence. Selected compounds were evaluated for their in vitro cytotoxicity against human tumor HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines. (C) 2012 Elsevier Ltd. All rights reserved. |
学科主题 | Chemistry |
类目[WOS] | Chemistry, Organic |
研究领域[WOS] | Chemistry |
关键词[WOS] | UNIQUE SKELETON ; LIGNANS ; ANANOSMA ; LONGIPEDUNCULATA ; DILACTONES ; INTERIOR ; STEMS ; ANGUSTIFOLIA ; HETEROCLITA ; COCCINEA |
收录类别 | SCI ; IC |
资助信息 | This work was supported financially by the NSFC (No. 30830115 to H.-D.S., and 20902093 to J.-X.P.), the Science and Technology Program of Yunnan Province (2008GA031), the Major State Basic Research Development Program of China (No. 2009CB522300), the Western Doctoral Foundation of Chinese Academy of Sciences (J.-X.P.), and the Reservation-Talent Project of Yunnan Province (J.-X.P.). |
语种 | 英语 |
WOS记录号 | WOS:000304798800031 |
公开日期 | 2014-04-02 |
内容类型 | 期刊论文 |
源URL | [http://ir.kib.ac.cn/handle/151853/17619] |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Yunnan Acad Tobacco Sci, Kunming 650106, Peoples R China |
推荐引用方式 GB/T 7714 | Dong, Ke,Pu, Jian-Xin,Du, Xue,et al. Kadpolysperins A-N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma[J]. TETRAHEDRON,2012,68(24):4820-4829. |
APA | Dong, Ke.,Pu, Jian-Xin.,Du, Xue.,Su, Jia.,Li, Xiao-Nian.,...&Sun, Han-Dong.(2012).Kadpolysperins A-N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma.TETRAHEDRON,68(24),4820-4829. |
MLA | Dong, Ke,et al."Kadpolysperins A-N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma".TETRAHEDRON 68.24(2012):4820-4829. |
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