Dielectric barrier discharge plasma in Ar/O-2 promoting apoptosis behavior in A549 cancer cells | |
Huang, J ; Li, H ; Chen, W ; Lv, GH ; Wang, XQ ; Zhang, GP ; Ostrikov, K ; Wang, PY ; Yang, SZ | |
刊名 | APPLIED PHYSICS LETTERS |
2011 | |
卷号 | 99期号:25 |
关键词 | ATMOSPHERIC-PRESSURE PLASMA BIOMEDICAL APPLICATIONS OXYGEN STERILIZATION BACTERIA DEATH |
ISSN号 | 0003-6951 |
通讯作者 | Huang, J: Chinese Acad Sci, Inst Phys, Beijing 100190, Peoples R China. |
中文摘要 | The Ar/O-2 plasma needle in the induction of A549 cancer cells apoptosis process is studied by means of real-time observation. The entire process of programmed cell death is observed. The typical morphological changes of A549 apoptosis are detected by 4', 6-diamidino-2-phenylindole staining, for example, chromatin condensation and nuclear fragmentation. Cell viability is determined and quantified by neutral red uptake assay, and the survival rate of A549 from Ar/O-2 plasmas is presented. Further spectral analysis indicates the reactive species, including O and OH play crucial roles in the cell inactivation. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3666819] |
收录类别 | SCI |
资助信息 | National Natural Science Foundation of China [10735090, 11005151]; Australian Research Council |
语种 | 英语 |
公开日期 | 2013-09-17 |
内容类型 | 期刊论文 |
源URL | [http://ir.iphy.ac.cn/handle/311004/35919] |
专题 | 物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文 |
推荐引用方式 GB/T 7714 | Huang, J,Li, H,Chen, W,et al. Dielectric barrier discharge plasma in Ar/O-2 promoting apoptosis behavior in A549 cancer cells[J]. APPLIED PHYSICS LETTERS,2011,99(25). |
APA | Huang, J.,Li, H.,Chen, W.,Lv, GH.,Wang, XQ.,...&Yang, SZ.(2011).Dielectric barrier discharge plasma in Ar/O-2 promoting apoptosis behavior in A549 cancer cells.APPLIED PHYSICS LETTERS,99(25). |
MLA | Huang, J,et al."Dielectric barrier discharge plasma in Ar/O-2 promoting apoptosis behavior in A549 cancer cells".APPLIED PHYSICS LETTERS 99.25(2011). |
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