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Dielectric barrier discharge plasma in Ar/O-2 promoting apoptosis behavior in A549 cancer cells
Huang, J ; Li, H ; Chen, W ; Lv, GH ; Wang, XQ ; Zhang, GP ; Ostrikov, K ; Wang, PY ; Yang, SZ
刊名APPLIED PHYSICS LETTERS
2011
卷号99期号:25
关键词ATMOSPHERIC-PRESSURE PLASMA BIOMEDICAL APPLICATIONS OXYGEN STERILIZATION BACTERIA DEATH
ISSN号0003-6951
通讯作者Huang, J: Chinese Acad Sci, Inst Phys, Beijing 100190, Peoples R China.
中文摘要The Ar/O-2 plasma needle in the induction of A549 cancer cells apoptosis process is studied by means of real-time observation. The entire process of programmed cell death is observed. The typical morphological changes of A549 apoptosis are detected by 4', 6-diamidino-2-phenylindole staining, for example, chromatin condensation and nuclear fragmentation. Cell viability is determined and quantified by neutral red uptake assay, and the survival rate of A549 from Ar/O-2 plasmas is presented. Further spectral analysis indicates the reactive species, including O and OH play crucial roles in the cell inactivation. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3666819]
收录类别SCI
资助信息National Natural Science Foundation of China [10735090, 11005151]; Australian Research Council
语种英语
公开日期2013-09-17
内容类型期刊论文
源URL[http://ir.iphy.ac.cn/handle/311004/35919]  
专题物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文
推荐引用方式
GB/T 7714
Huang, J,Li, H,Chen, W,et al. Dielectric barrier discharge plasma in Ar/O-2 promoting apoptosis behavior in A549 cancer cells[J]. APPLIED PHYSICS LETTERS,2011,99(25).
APA Huang, J.,Li, H.,Chen, W.,Lv, GH.,Wang, XQ.,...&Yang, SZ.(2011).Dielectric barrier discharge plasma in Ar/O-2 promoting apoptosis behavior in A549 cancer cells.APPLIED PHYSICS LETTERS,99(25).
MLA Huang, J,et al."Dielectric barrier discharge plasma in Ar/O-2 promoting apoptosis behavior in A549 cancer cells".APPLIED PHYSICS LETTERS 99.25(2011).
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