Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers

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	Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers
	Gu, Wei1,2 ; Hao, Xiao-Jiang3 ; Liu, Hong-Xin 1,2; Wang, Yue-Hu1 ; Long, Chun-Lin 1,4
刊名	PHYTOCHEMISTRY LETTERS
	2013-11-01
卷号	6 期号:4 页码:681-685
关键词	Gmelina arborea Iridoid glycosides Acylated rhamnopyranoses Phenylethanoid Cytoprotective activity
ISSN号	1874-3900
通讯作者	Long,CL (reprint author),Minzu Univ China,Coll Life & Environm Sci,Beijing 100081,Peoples R China.,wangyuehu@mail.kib.ac.cn ; long@mail.kib.ac.cn
英文摘要	Nine acylated iridoid glycosides (1-9), five acylated rhamnopyranoses (10-14) and verbascoside (15) were isolated from Gmelina arborea flowers, including 5 new compounds (1, 2, and 10-12). The cytoprotective activity of 11 selected compounds (1-8, 10, 11, and 15) against CCl4-induced cytotoxicity on liver was determined. Compounds 1, 2, 4, 7, 8 and 15 displayed hepatoprotective activity. 6-O-alpha-L-(2 '',3 ''-di-O-trans-p-hydroxycinnamoyl)rhamnopyranosylcatalpol (2) exhibited the most potent cytoprotective effect with an EC50 value of 42.5 mu M (SI = 19.3) compared with biphenyldimethylesterate (DDB, EC50 = 277.3 mu M, SI = 9.8) and bicylo-ethanol (EC50 = 279.2 mu M, SI = 12.2). Among the acylated iridoid glycosides, the compounds (2 and 8) containing phenolic hydroxy groups were more active than were those lacking them. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
学科主题	Biochemistry & Molecular Biology ; Plant Sciences
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Biochemistry & Molecular Biology ; Plant Sciences
研究领域[WOS]	Biochemistry & Molecular Biology ; Plant Sciences
关键词[WOS]	PREMNA-JAPONICA ; ANTIFUNGAL ACTIVITY ; LEAVES ; HEARTWOOD ; LIGNANS ; LINN ; 6-O-ALPHA-L-RHAMNOPYRANOSYLCATALPOL ; CONSTITUENTS
收录类别	SCI
语种	英语
WOS记录号	WOS:000325872700038
公开日期	2014-01-13
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/17435]
专题	昆明植物研究所_资源植物与生物技术所级重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, Key Lab Econ Plants & Biotechnol, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 4.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China
推荐引用方式 GB/T 7714	Gu, Wei,Hao, Xiao-Jiang,Liu, Hong-Xin,et al. Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers[J]. PHYTOCHEMISTRY LETTERS,2013,6(4):681-685.
APA	Gu, Wei,Hao, Xiao-Jiang,Liu, Hong-Xin,Wang, Yue-Hu,&Long, Chun-Lin.(2013).Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers.PHYTOCHEMISTRY LETTERS,6(4),681-685.
MLA	Gu, Wei,et al."Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers".PHYTOCHEMISTRY LETTERS 6.4(2013):681-685.