Aestivation in Nature: Physiological Strategies and Evolutionary Adaptations in Hypometabolic States

doi:10.3390/ijms241814093

CORC > 海洋研究所 > 中国科学院海洋研究所 > 海洋生态与环境科学重点实验室

	Aestivation in Nature: Physiological Strategies and Evolutionary Adaptations in Hypometabolic States
	Jiang, Chunxi 2,3,4; Storey, Kenneth B.1; Yang, Hongsheng 2,3,4; Sun, Lina 2,3,4
刊名	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
	2023-09-01
卷号	24 期号:18 页码:25
关键词	aestivation hypometabolic states physiological strategies regulatory network
ISSN号	1661-6596
DOI	10.3390/ijms241814093
通讯作者	Sun, Lina(sunlina@qdio.ac.cn)
英文摘要	Aestivation is considered to be one of the "purest" hypometabolic states in nature, as it involves aerobic dormancy that can be induced and sustained without complex factors. Animals that undergo aestivation to protect themselves from environmental stressors such as high temperatures, droughts, and food shortages. However, this shift in body metabolism presents new challenges for survival, including oxidative stress upon awakening from aestivation, accumulation of toxic metabolites, changes in energy sources, adjustments to immune status, muscle atrophy due to prolonged immobility, and degeneration of internal organs due to prolonged food deprivation. In this review, we summarize the physiological and metabolic strategies, key regulatory factors, and networks utilized by aestivating animals to address the aforementioned components of aestivation. Furthermore, we present a comprehensive overview of the advancements made in aestivation research across major species, including amphibians, fish, reptiles, annelids, mollusks, and echinoderms, categorized according to their respective evolutionary positions. This approach offers a distinct perspective for comparative analysis, facilitating an understanding of the shared traits and unique features of aestivation across different groups of organisms.
资助项目	National Natural Science Foundation of China[42076093] ; National Natural Science Foundation of China[42276143] ; Taishan Scholars Program
WOS关键词	CUCUMBER APOSTICHOPUS-JAPONICUS ; AFRICAN CLAWED FROG ; STRIPED BURROWING FROG ; LUNGFISH PROTOPTERUS-ANNECTENS ; HORMOGASTER-ELISAE OLIGOCHAETA ; DIFFERENTIAL GENE-EXPRESSION ; INCREASED UREA SYNTHESIS ; AMINO-ACID-METABOLISM ; SNAIL THEBA-PISANA ; SEA-CUCUMBER
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
出版者	MDPI
WOS记录号	WOS:001145166800001
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/184395]
专题	海洋研究所_海洋生态与环境科学重点实验室
通讯作者	Sun, Lina
作者单位	1.Carleton Univ, Dept Biol, Ottawa, ON K1S 5B6, Canada 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci & Marine Biol & Bio, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci & Expt Mari, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Jiang, Chunxi,Storey, Kenneth B.,Yang, Hongsheng,et al. Aestivation in Nature: Physiological Strategies and Evolutionary Adaptations in Hypometabolic States[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2023,24(18):25.
APA	Jiang, Chunxi,Storey, Kenneth B.,Yang, Hongsheng,&Sun, Lina.(2023).Aestivation in Nature: Physiological Strategies and Evolutionary Adaptations in Hypometabolic States.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,24(18),25.
MLA	Jiang, Chunxi,et al."Aestivation in Nature: Physiological Strategies and Evolutionary Adaptations in Hypometabolic States".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 24.18(2023):25.