In recent years, soft and stretchable electronics are emerging as part of a new generation of electronic devices. Owing to their unprecedented material propertiesdsoftness, flexibility, and stretchabilitydcompared to conventional electronics, they enable innovative applications such as flexible lighting, skin electronics, soft robotics, and flexible energy storage. Here, we review the strategies that made these inventions possible. The first approach is to synthesize stretchable materials that are either intrinsically stretchable or stretchable at a macroscale. The second approach is to use materials that lack the inherent stretchability or flexibility required, but instead to induce the necessary properties through carefully structuring. Afterward, some of the representative soft and stretchable sensors made possible using these strategies are explored. Finally, this review concludes with the limitation of the existing soft and stretchable electronics and some suggestions for possible future development.