Applications of Near-Infrared Fluorescence Imaging and Angiography of Inferior Vesical Artery in Laparoscopic Lateral Lymph Node Dissection: A Prospective Nonrandomized Controlled Study

doi:10.1097/DCR.0000000000002926

CORC > 自动化研究所 > 中国科学院自动化研究所 > 中国科学院分子影像重点实验室

	Applications of Near-Infrared Fluorescence Imaging and Angiography of Inferior Vesical Artery in Laparoscopic Lateral Lymph Node Dissection: A Prospective Nonrandomized Controlled Study
	Tang, Bin 2; Zhou, Sicheng 3; He, Kunshan 4; Mei, Shiwen 2; Qiu, Wenlong 2; Guan, Xu 2; Liu, Fucheng 5; Chi, Chongwei 6; Wang, Xishan 2; Tian, Jie 1,4,6
刊名	DISEASES OF THE COLON & RECTUM
	2024
卷号	67 期号:1 页码:175-184
关键词	Indocyanine green Inferior vesical artery Lateral lymph node dissection Near-infrared imaging Rectal cancer Urinary function
ISSN号	0012-3706
DOI	10.1097/DCR.0000000000002926
通讯作者	Tian, Jie(jie.tian@ia.ac.cn) ; Liu, Qian() ; Tang, Jianqiang(doc_tjq@hotmail.com)
英文摘要	BACKGROUND: Near-infrared imaging with indocyanine green has been used to guide lateral lymph node dissection, yet its efficacy and benefits need further investigation.OBJECTIVE: To investigate the efficacy and feasibility of near-infrared fluorescence imaging and angiography of the inferior vesical artery in laparoscopic lateral lymph node dissection.DESIGN: A prospective nonrandomized controlled study.SETTINGS: Single-center study.PATIENTS: Patients with lower rectal cancer who underwent total mesorectal excision plus lateral lymph node dissection.MAIN OUTCOME MEASURES: A cohort of 108 patients was enrolled. After propensity score matching, 29 patients in the near-infrared group and 50 patients in the non-near-infrared group were matched. The total number of harvested lateral lymph nodes, positive lateral lymph nodes, inferior vesical artery preservation, and postoperative urinary function were compared.RESULTS: After propensity score matching, both groups had similar baseline characteristics. The total number of harvested lateral lymph nodes in the near-infrared group was significantly higher (12 vs 9, p = 0.013), but positive lateral lymph nodes were similar between the 2 groups (1 vs 1, p = 0.439). The inferior vesical artery preservation ratio was significantly increased with the aid of indocyanine green angiography (93.1% vs 56.0%, p < 0.001). The non-near-infrared group required more days for urinary catheter removal than the near-infrared group (5 vs 4, p = 0.046). Urinary recatheterization tended to occur more frequently in the non-near-infrared group, with a marginally significant trend (16% vs 0%, p = 0.059). The non-near-infrared group tended to have more cases with residual urine volume >= 50 mL than the near-infrared group (20.0% vs 3.4%, p = 0.087), especially in the bilateral dissection subgroup (41.2% vs 0%, p = 0.041).LIMITATIONS: Small sample size.CONCLUSIONS: Near-infrared imaging increased the number of harvested lateral lymph nodes, whereas real-time indocyanine green fluorescence angiography ensured the preservation of the inferior vesical artery and tended to improve postoperative urinary function.
资助项目	Wu Jieping Special Foundation for Clinical Research[320.6750.2021-04-02] ; The Hope Star Project of Cancer Hospital of Chinese Academy of Medical Sciences ; National Key R&D Program for Young Scientists[SQ2022YFC2500011] ; National Natural Science Foundation of China[62027901] ; National Natural Science Foundation of China[81227901] ; National Natural Science Foundation of China[81930053] ; National Natural Science Foundation of China[82001984] ; National Natural Science Foundation of China[92059207] ; National Natural Science Foundation of China[92059203] ; Beijing Natural Science Foundation[L222054]
WOS关键词	LOWER RECTAL-CANCER ; INDOCYANINE GREEN ; MESORECTAL EXCISION ; COMBINED RESECTION ; ILIAC VESSELS ; SURGERY ; FASCIA
WOS研究方向	Gastroenterology & Hepatology ; Surgery
语种	英语
出版者	LIPPINCOTT WILLIAMS & WILKINS
WOS记录号	WOS:001131654300015
资助机构	Wu Jieping Special Foundation for Clinical Research ; The Hope Star Project of Cancer Hospital of Chinese Academy of Medical Sciences ; National Key R&D Program for Young Scientists ; National Natural Science Foundation of China ; Beijing Natural Science Foundation
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/54826]
专题	自动化研究所_中国科学院分子影像重点实验室
通讯作者	Tian, Jie; Liu, Qian; Tang, Jianqiang
作者单位	1.95 Zhongguancun E Rd, Beijing 100000, Peoples R China 2.Chinese Acad Med Sci & Peking Union Med Coll, Canc Hosp, Dept Colorectal Surg, Natl Clin Res Ctr Canc,Natl Canc Ctr, Beijing, Peoples R China 3.Peking Univ First Hosp, Breast Dis Ctr, Beijing, Peoples R China 4.Beihang Univ, Beijing Adv Innovat Ctr Big Data Based Precis Med, Sch Med & Engn, Beijing, Peoples R China 5.Fengtai Hosp, Dept Gen Surg, Beijing, Peoples R China 6.Chinese Acad Sci, CAS Key Lab Mol Imaging, State Key Lab Management & Control Complex Syst, Beijing Key Lab Mol Imaging,Inst Automat, Beijing, Peoples R China 7.17 Panjiayuan Nanli, Beijing 100021, Peoples R China
推荐引用方式 GB/T 7714	Tang, Bin,Zhou, Sicheng,He, Kunshan,et al. Applications of Near-Infrared Fluorescence Imaging and Angiography of Inferior Vesical Artery in Laparoscopic Lateral Lymph Node Dissection: A Prospective Nonrandomized Controlled Study[J]. DISEASES OF THE COLON & RECTUM,2024,67(1):175-184.
APA	Tang, Bin.,Zhou, Sicheng.,He, Kunshan.,Mei, Shiwen.,Qiu, Wenlong.,...&Tang, Jianqiang.(2024).Applications of Near-Infrared Fluorescence Imaging and Angiography of Inferior Vesical Artery in Laparoscopic Lateral Lymph Node Dissection: A Prospective Nonrandomized Controlled Study.DISEASES OF THE COLON & RECTUM,67(1),175-184.
MLA	Tang, Bin,et al."Applications of Near-Infrared Fluorescence Imaging and Angiography of Inferior Vesical Artery in Laparoscopic Lateral Lymph Node Dissection: A Prospective Nonrandomized Controlled Study".DISEASES OF THE COLON & RECTUM 67.1(2024):175-184.