海藻寡糖的化学法降解制备技术研究进展
孙林1,2; 宋宛霖1,2; 钟志海1,2; 刘正一1,2
刊名大连工业大学学报
2023
卷号42期号:6页码:427-433
关键词海藻寡糖 化学法降解 规模化制备 精准制
ISSN号1674-1404
其他题名Application of alginate hydrogel as a delivery vehicle in tissue regeneration
文献子类期刊论文
英文摘要Alginate is a class of linear hydrophilic polysaccharides found in brown algae.It is composed of repeating units of D-mannuronic acid (M) and L-guluronic acid (G) in different proportions.It is one of the natural biological materials used for hydrogel synthesis.Through simple ion cross-linking,it can react with Ca~(2+) and other multivalent inorganic cations to form hydrogel,which called egg box reaction.There are a large number of-OH and-COOH polar groups on the alginate skeleton,which can be modified by chemical or physical methods to achieve controlled release of cells or biologically active molecules in response to temperature,pH,light and other stimuli.At present,one of the main application strategies in the field of tissue regeneration is to use biocompatible materials,combined with bioactive molecules and cells,to promote the regeneration of damaged tissues.Hydrogel materials have the potential to protect embedded cells and mimic the natural extracellular matrix.Alginate is also widely used in the field of tissue regeneration due to its easy gelation and good biocompatibility.In this review,we summarized the different crosslinking methods of alginate hydrogels,focusing on the characteristics of alginate hydrogels that are responsive to stimuli and their applications as delivery vehicles in tissue regeneration.
语种中文
CSCD记录号CSCD:7176917
内容类型期刊论文
源URL[http://ir.yic.ac.cn/handle/133337/34094]  
专题海岸带生物学与生物资源利用重点实验室
作者单位1.中国科学院烟台海岸带研究所,山东烟台264003;
2.中国科学院海洋大科学研究中心,山东青岛266071
推荐引用方式
GB/T 7714
孙林,宋宛霖,钟志海,等. 海藻寡糖的化学法降解制备技术研究进展[J]. 大连工业大学学报,2023,42(6):427-433.
APA 孙林,宋宛霖,钟志海,&刘正一.(2023).海藻寡糖的化学法降解制备技术研究进展.大连工业大学学报,42(6),427-433.
MLA 孙林,et al."海藻寡糖的化学法降解制备技术研究进展".大连工业大学学报 42.6(2023):427-433.
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