The unconventional prefoldin RPB5 interactor mediates the gravitropic response by modulating cytoskeleton organization and auxin transport in Arabidopsis

doi:10.1111/jipb.13341

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	The unconventional prefoldin RPB5 interactor mediates the gravitropic response by modulating cytoskeleton organization and auxin transport in Arabidopsis
	Yang, Yi 2,7; Liu, Fang 8; Liu, Le 8; Zhu, Mingyue 7; Yuan, Jinfeng 7; Mai, Yan-Xia ; Zou, Jun-Jie ; Le, Jie 4,5; Wang, Yonghong ; Palme, Klaus 7,8
刊名	JOURNAL OF INTEGRATIVE PLANT BIOLOGY
	2022
卷号	64 期号:10 页码:1916-1934
关键词	Arabidopsis auxin cytoskeleton PIN2 prefoldin (PFD) unconventional prefoldin RPB5 interactor (URI)
ISSN号	1672-9072
DOI	10.1111/jipb.13341
文献子类	Article
英文摘要	Gravity-induced root curvature involves the asymmetric distribution of the phytohormone auxin. This response depends on the concerted activities of the auxin transporters such as PIN-FORMED (PIN) proteins for auxin efflux and AUXIN RESISTANT 1 (AUX1) for auxin influx. However, how the auxin gradient is established remains elusive. Here we identified a new mutant with a short root, strong auxin distribution in the lateral root cap and an impaired gravitropic response. The causal gene encoded an Arabidopsis homolog of the human unconventional prefoldin RPB5 interactor (URI). AtURI interacted with prefoldin 2 (PFD2) and PFD6, two beta-type PFD members that modulate actin and tubulin patterning in roots. The auxin reporter DR5(rev):GFP showed that asymmetric auxin redistribution after gravistimulation is disordered in aturi-1 root tips. Treatment with the endomembrane protein trafficking inhibitor brefeldin A indicated that recycling of the auxin transporter PIN2 is disrupted in aturi-1 roots as well as in pfd mutants. We propose that AtURI cooperates with PFDs to recycle PIN2 and modulate auxin distribution.
学科主题	Biochemistry & Molecular Biology ; Plant Sciences
电子版国际标准刊号	1744-7909
出版地	HOBOKEN
WOS关键词	ACTIN CYTOSKELETON ; MOLECULAR-MECHANISMS ; ROOT GRAVITROPISM ; CAP CELLS ; EFFLUX ; PROTEIN ; THALIANA ; PIN2 ; INHIBITORS ; DYNAMICS
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
语种	英语
出版者	WILEY
WOS记录号	WOS:000859050500001
资助机构	Shandong Agricultural University ; National Natural Science Foundation of China [31570291] ; Natural Science Foundation of Shandong Province [ZR2021MC175] ; Shandong Foreign experts double hundred Program [WST2017008]
内容类型	期刊论文
源URL	[http://ir.ibcas.ac.cn/handle/2S10CLM1/28533]
专题	中科院植物分子生理学重点实验室
作者单位	1.Albert Ludwigs Univ Freiburg, Fac Biol, Inst Biol Mol Plant Physiol 2, Schanzlestr 1, D-79104 Freiburg, Germany 2.Shandong Agr Univ, Coll Life Sci, State Key Lab Crop Biol, Daizong St 61, Tai An 271018, Shandong, Peoples R China 3.Chinese Acad Sci, CAS Ctr Excellence Mol Plant Sci, Inst Plant Physiol & Ecol SIPPE, Natl Key Lab Plant Mol Genet NKLPMG, Shanghai 200032, Peoples R China 4.Chinese Acad Agr Sci, Biotechnol Res Inst, Beijing 100081, Peoples R China 5.Chinese Acad Sci, CAS Ctr Excellence Mol Plant Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China 6.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 7.Dezhou Univ, Inst Biophys, Shandong Prov Key Lab Biophys, Dezhou 253023, Peoples R China 8.Shandong Agr Univ, Coll Life Sci, Sino German Joint Res Ctr Agr Biol, Daizong St 61, Tai An 271018, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Yang, Yi,Liu, Fang,Liu, Le,et al. The unconventional prefoldin RPB5 interactor mediates the gravitropic response by modulating cytoskeleton organization and auxin transport in Arabidopsis[J]. JOURNAL OF INTEGRATIVE PLANT BIOLOGY,2022,64(10):1916-1934.
APA	Yang, Yi.,Liu, Fang.,Liu, Le.,Zhu, Mingyue.,Yuan, Jinfeng.,...&Wang, Long.(2022).The unconventional prefoldin RPB5 interactor mediates the gravitropic response by modulating cytoskeleton organization and auxin transport in Arabidopsis.JOURNAL OF INTEGRATIVE PLANT BIOLOGY,64(10),1916-1934.
MLA	Yang, Yi,et al."The unconventional prefoldin RPB5 interactor mediates the gravitropic response by modulating cytoskeleton organization and auxin transport in Arabidopsis".JOURNAL OF INTEGRATIVE PLANT BIOLOGY 64.10(2022):1916-1934.