Astaxanthin production from the microalga Haematococcus lacustris with a dual substrate mixotrophy strategy

doi:10.1002/biot.202300095

CORC > 海洋研究所 > 中国科学院海洋研究所 > 实验海洋生物学重点实验室

	Astaxanthin production from the microalga Haematococcus lacustris with a dual substrate mixotrophy strategy
	Khazi, Mahammed Ilyas 4; Liaqat, Fakhra 4; Gu, Wenhui 3; Mohamed, Badr 2; Zhu, Daochen 1; Li, Jian 4
刊名	BIOTECHNOLOGY JOURNAL
	2023-06-28
页码	11
关键词	acetate astaxanthin dual-substrate mixotrophic cultivation pyruvate
ISSN号	1860-6768
DOI	10.1002/biot.202300095
通讯作者	Li, Jian(lij@pzhu.edu.cn)
英文摘要	This study investigates the development of dual-substrate mixotrophy strategy to cultivate the microalga Haematococcus lacustris for astaxanthin production. The influence of different concentrations of acetate and pyruvate on biomass productivity was first assessed individually, and then both substrates were used together to improve biomass growth in the green phase and astaxanthin accumulation in red the phase. The results showed that dual-substrates mixotrophy significantly increased the biomass productivity during green growth phase up to 2-fold compared to phototrophic controls. Furthermore, supplementation of dual-substrate to the red phase increased astaxanthin accumulation by 10% in the dual-substrate group compared to single-substrate acetate and no substrate. This dual-substrate mixotrophy approach shows promise for cultivating Haematococcus for commercial production of biological astaxanthin in indoor closed systems.
资助项目	Science and Technology Innovation Base and Talent Program in Sichuan Province, China[2022JDGD0026] ; Key Research and Development Program of Jiangsu Province, China[BE2021691]
WOS关键词	LIGHT-INTENSITY ; GREEN-ALGA ; PLUVIALIS ; ACETATE ; GROWTH ; ACCUMULATION ; CARBON ; CULTIVATION ; CULTURES ; GLUCOSE
WOS研究方向	Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:001015858800001
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/182382]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Li, Jian
作者单位	1.Jiangsu Univ, Biofuels Inst, Sch Emergency Management, Sch Environm & Safety Engn, Zhenjiang, Peoples R China 2.Cairo Univ, Dept Agr Engn, Giza, Egypt 3.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China 4.Panzhihua Univ, Coll Biol & Chem Engn, Coll Agr Sci, Panzhihua, Peoples R China
推荐引用方式 GB/T 7714	Khazi, Mahammed Ilyas,Liaqat, Fakhra,Gu, Wenhui,et al. Astaxanthin production from the microalga Haematococcus lacustris with a dual substrate mixotrophy strategy[J]. BIOTECHNOLOGY JOURNAL,2023:11.
APA	Khazi, Mahammed Ilyas,Liaqat, Fakhra,Gu, Wenhui,Mohamed, Badr,Zhu, Daochen,&Li, Jian.(2023).Astaxanthin production from the microalga Haematococcus lacustris with a dual substrate mixotrophy strategy.BIOTECHNOLOGY JOURNAL,11.
MLA	Khazi, Mahammed Ilyas,et al."Astaxanthin production from the microalga Haematococcus lacustris with a dual substrate mixotrophy strategy".BIOTECHNOLOGY JOURNAL (2023):11.