A rapid extraction process monitoring of Swertia mussotii Franch. With near infrared spectroscopy

	A rapid extraction process monitoring of Swertia mussotii Franch. With near infrared spectroscopy
	Zhang, Mengqi; Zhao, Bing; Li, Lian; Nie, Lei; Li, Peipei; Sun, Jing; Wu, Aoli; Zang, Hengchang
刊名	SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
	2023
卷号	295
英文摘要	Swertia mussotii Franch. (SMF), a traditional Tibetan medicine, which has miraculous effect on treating hepatitis diseases. However, there is no research on its entire production process, and invisible production process has seriously hindered the SMF modern development. In this study, principal component analysis (PCA), subtractive spectroscopy, and two-dimensional correlation spectroscopy (2D-COS) were used to explain changes of char-acteristic groups in the extraction process. Four main characteristic peaks at 1884 nm, 1944 nm, 2246 nm and 2308 nm were identified to describe the changes of molecular structure information of total active components in SMF extraction process. In addition, multi critical quality attributes (CQAs) models were established by near -infrared spectroscopy (NIRS) combined with the total quantum statistical moment (TQSM). The coefficients of determination (R2eval and R2ival) were both greater than 0.99. The ratios of the standard deviation of validation to the standard error of the prediction (RPDe and RPDi) were greater than five. The quantitative model of AUCT could save time on primary data measurement by not requiring determination of indicator components compared with others. In conclusion, these results demonstrated that it was feasible to understand the SMF extraction process through AUCT and characteristic groups. These could realize the visual digital characterization and quality stability of the SMF extraction process.
内容类型	期刊论文
源URL	[http://210.75.249.4/handle/363003/61679]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Zhang, Mengqi,Zhao, Bing,Li, Lian,et al. A rapid extraction process monitoring of Swertia mussotii Franch. With near infrared spectroscopy[J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,2023,295.
APA	Zhang, Mengqi.,Zhao, Bing.,Li, Lian.,Nie, Lei.,Li, Peipei.,...&Zang, Hengchang.(2023).A rapid extraction process monitoring of Swertia mussotii Franch. With near infrared spectroscopy.SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,295.
MLA	Zhang, Mengqi,et al."A rapid extraction process monitoring of Swertia mussotii Franch. With near infrared spectroscopy".SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 295(2023).