The temporal variations of solar rotation in the photosphere, chromosphere, and corona have been widely investigated, whereas the rotation of the solar transition region is rarely studied. Here, we perform a primary study about the long-term variation of the rotation in the transition region using Ly & alpha; irradiance from 1947 February 14 to 2023 February 20. Correlation techniques are used, and the main results are as follows. (1) The sidereal rotation period of the solar transition region varies between 22.24 and 31.49 days, and the mean sidereal rotation period is 25.50 days for the studied time interval 1947-2022. (2) The rotation period of the transition region exhibits a clear downward trend during 1947-2022, which might be caused by the reduced heliospheric pressure and the weaker solar global magnetic fields. (3) Significant periodic signal of the quasi-Schwabe cycle is found in the rotation periods of the transition region. (4) The cross-correlation between the rotation periods of the solar transition region and sunspot activity corroborates a strong correlation with the Schwabe cycle. Possible mechanisms responsible for these results are discussed.