Structure elucidation and in vitro rat intestinal fermentation properties of a novel sulfated glucogalactan from Porphyra haitanensis

doi:10.1016/j.fshw.2022.07.062

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室

	Structure elucidation and in vitro rat intestinal fermentation properties of a novel sulfated glucogalactan from Porphyra haitanensis
	Chen, Peilin 3,4; Liu, Lu 3; Cheng, Zirun 3; Zhang, Yi 2,3,4; Zheng, Baodong 2,3,4; Hu, Xiaoke 1; Zeng, Hongliang 2,3,4
刊名	FOOD SCIENCE AND HUMAN WELLNESS
	2023-03-01
卷号	12 期号:2 页码:596-606
关键词	Porphyra haitanensis Structure characterization Fecal microflora Short-chain fatty acids Metabolic function prediction Polysaccharide
DOI	10.1016/j.fshw.2022.07.062
英文摘要	This study was to investigate the structure and rat fecal microbial fermentation properties of a polysaccharide fraction (PHP2) isolated from the red marine alga Porphyra haitanensis. PHP2 was characterized as a sulfated glucogalactan, with a hypothetical backbone structure of -> 4)G alpha(1 -> 6)G4S beta(1 -> 4)Glc(1 -> and a side chain of Man(1 -> 6)Glc. PHP2 had an irregular spherical chain conformation. The 16S rRNA sequence analysis revealed that PHP2 modulated the rat fecal micro-fl ora composition, with a similar effect to inulin, changing the dominant genus (Lactobacillus and Escherichia-Shigella) and promoting the growth of organisms that degrade sulfur-containing polysaccharides, such as Desulfovibrio, Ruminococcaceae_UCG-005, and Ruminococcus_2. PHP2 can promote production of acetic, propionic and butyric acid by rat fecal micro-flora. Prediction of metabolic function suggested that PHP2 could modulate cholesterol metabolism. The sulfated glucogalactan fermentation behavior may be associated with its monosaccharide composition, chain branching and chain conformation. PHP2 appeared to have considerable potential as functional food, and was associated with sulfur-containing polysaccharides in general. (C) 2023 Beijing Academy of Food Sciences. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.
资助项目	Scientific Research Foundation of Graduate School of Fujian Agriculture and Forestry University[1122yb065] ; Program for Leading Talent in Fujian Provincial University[660160190]
WOS关键词	IMMUNOMODULATORY ACTIVITY ; MICROBIAL CATABOLISM ; SIMULATED DIGESTION ; CHAIN CONFORMATION ; KAPPA-CARRAGEENAN ; RESISTANT STARCH ; GUT MICROBIOTA ; POLYSACCHARIDE ; OLIGOSACCHARIDES ; PURIFICATION
WOS研究方向	Food Science & Technology ; Nutrition & Dietetics
语种	英语
出版者	KEAI PUBLISHING LTD
WOS记录号	WOS:000862039500001
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/31726]
专题	海岸带生物学与生物资源利用重点实验室
通讯作者	Hu, Xiaoke; Zeng, Hongliang
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 2.Fujian Agr & Forestry Univ, Fujian Prov Key Lab Qual Sci & Proc Technol Specia, Fuzhou 350002, Peoples R China 3.Fujian Agr & Forestry Univ, Coll Food Sci, Fuzhou 350002, Peoples R China 4.Minist Educ, Engn Res Ctr, Fujian Taiwan Special Marine Food Proc & Nutr, Fuzhou 350002, Peoples R China
推荐引用方式 GB/T 7714	Chen, Peilin,Liu, Lu,Cheng, Zirun,et al. Structure elucidation and in vitro rat intestinal fermentation properties of a novel sulfated glucogalactan from Porphyra haitanensis[J]. FOOD SCIENCE AND HUMAN WELLNESS,2023,12(2):596-606.
APA	Chen, Peilin.,Liu, Lu.,Cheng, Zirun.,Zhang, Yi.,Zheng, Baodong.,...&Zeng, Hongliang.(2023).Structure elucidation and in vitro rat intestinal fermentation properties of a novel sulfated glucogalactan from Porphyra haitanensis.FOOD SCIENCE AND HUMAN WELLNESS,12(2),596-606.
MLA	Chen, Peilin,et al."Structure elucidation and in vitro rat intestinal fermentation properties of a novel sulfated glucogalactan from Porphyra haitanensis".FOOD SCIENCE AND HUMAN WELLNESS 12.2(2023):596-606.