Qualitative and quantitative determination of butanol in latex paint by fast gas chromatography proton transfer reaction mass spectrometry

doi:10.1016/j.chroma.2022.463210

	Qualitative and quantitative determination of butanol in latex paint by fast gas chromatography proton transfer reaction mass spectrometry
	Sun, Qin 1,2; Bao, Xun 1,2; Liang, Qu 1,2; Xu, Wei 1,2; Zhang, Qiangling 2; Zou, Xue 2; Huang, Chaoqun 2; Shen, Chengyin 2; Chu, Yannan 2
刊名	JOURNAL OF CHROMATOGRAPHY A
	2022-08-02
卷号	1676
关键词	FastGC-PTR-MS Butanol Isomer Resolution Retention time
ISSN号	0021-9673
DOI	10.1016/j.chroma.2022.463210
通讯作者	Zou, Xue(xzou@cmpt.ac.cn) ; Shen, Chengyin(chyshen@aiofm.ac.cn)
英文摘要	Butanol is a common organic solvent used in latex paint, and one of its isomers, tert-butanol, is toxic and can cause potential harm to the human body. Therefore, it is of great significance to develop a qualitative and quantitative detection method for butanol isomers. In this study, we combined the advantages of rapid detection of proton transfer reaction mass spectrometry (PTR-MS) with the separation and qualitative capabilities of gas chromatography-mass spectrometry (GC-MS) to achieve the detection of isomers, building a fast gas chromatography proton transfer reaction mass spectrometry (FastGC-PTR-MS) equipment. Firstly, the developed technology was optimized using standard samples of several common volatile organic compounds. The retention times of acetonitrile, acetone, and alcohols were less than 50 s, and the retention times of the benzene series were less than 110 s, on the premise that these isomers could be basically separated (resolution R > 1.0). Compared with a commercial GC-MS equipment, the detection times were shortened by 5-6 times and 2-4 times, respectively. Then the FastGC-PTR-MS was applied to detect the isomers of butanol in latex paint. The results showed that the headspace of brand D latex paint mainly contained five substances: tert-butanol, n-butanol, acetaldehyde, methanol, and acetone. Tert-butanol and n-butanol could be completely separated ( R > 1.5). The concentration of tert-butanol was 4.41 ppmv, far below the 100 ppmv maximum allowable workplace concentration. The developed FastGC-PTR-MS can be used for rapid qualitative and quantitative detection of butanol isomers in latex paint. The new equipment has the potential to play an important role in indoor environmental safety applications.
资助项目	National Natural Science Foundation of China[22076190] ; National Natural Science Foundation of China[21876176] ; National Natural Science Foundation of China[21777163] ; National Natural Science Foundation of China[21705152] ; National Natural Science Foundation of China[62171433] ; Youth Innovation Promotion Association, CAS, China[2019432] ; Anhui Provincial Key RD Program[202104d07020 0 03] ; HFIPS Director's Fund[BJPY2021B08] ; HFIPS Director's Fund[YZJJ2022QN45] ; Second Affiliated Hospital of Anhui Medical University ; Center of Medical Physics and Technology of Hefei Institute of Physical Sciences of Chinese Academy of Sciences[LHJJ2020 0 06]
WOS关键词	VOLATILE ORGANIC-COMPOUNDS ; PTR-MS ; TERTIARY-BUTANOL ; EMISSIONS ; ETHANOL ; ONLINE ; BVOCS ; VOCS
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000834927200014
资助机构	National Natural Science Foundation of China ; Youth Innovation Promotion Association, CAS, China ; Anhui Provincial Key RD Program ; HFIPS Director's Fund ; Second Affiliated Hospital of Anhui Medical University ; Center of Medical Physics and Technology of Hefei Institute of Physical Sciences of Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/132196]
专题	中国科学院合肥物质科学研究院
通讯作者	Zou, Xue; Shen, Chengyin
作者单位	1.Univ Sci & Technol China, Hefei 230026, Peoples R China 2.Chinese Acad Sci, Hefei Inst Phys Sci, Hefei 230031, Peoples R China
推荐引用方式 GB/T 7714	Sun, Qin,Bao, Xun,Liang, Qu,et al. Qualitative and quantitative determination of butanol in latex paint by fast gas chromatography proton transfer reaction mass spectrometry[J]. JOURNAL OF CHROMATOGRAPHY A,2022,1676.
APA	Sun, Qin.,Bao, Xun.,Liang, Qu.,Xu, Wei.,Zhang, Qiangling.,...&Chu, Yannan.(2022).Qualitative and quantitative determination of butanol in latex paint by fast gas chromatography proton transfer reaction mass spectrometry.JOURNAL OF CHROMATOGRAPHY A,1676.
MLA	Sun, Qin,et al."Qualitative and quantitative determination of butanol in latex paint by fast gas chromatography proton transfer reaction mass spectrometry".JOURNAL OF CHROMATOGRAPHY A 1676(2022).