Effects of 10 T static magnetic field on the function of sperms and their offspring in Caenorhabditis elegans

doi:10.1016/j.ecoenv.2022.113671

	Effects of 10 T static magnetic field on the function of sperms and their offspring in Caenorhabditis elegans
	Yang, Baolin 2,3,4; Yang, Zhen 2,3; Cheng, Lei 2,3,4; Li, Yang 2,3,4; Zhou, Tong 2,3; Han, Yuyan 1; Du, Hua 2,3; Xu, An 2,3,4
刊名	ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
	2022-07-01
卷号	240
关键词	10 T SMF Caenorhabditis elegans Sperm Function Offspring
ISSN号	0147-6513
DOI	10.1016/j.ecoenv.2022.113671
通讯作者	Du, Hua(huadu@ipp.ac.cn) ; Xu, An(anxu@ipp.ac.cn)
英文摘要	With the wide application of static magnetic fields (SMFs), the risk of living organisms exposed to man-made magnetic fields that the intensity is much higher than geomagnetic field has gradually increased. Reproductive system is highly sensitive to environmental stress; however, the influence of high SMFs on reproduction system is still largely unknown. Here we explored the biological responses of SMFs exposure at an intensity of 10 T on the sperms and their offspring in him-5 male mutants of Caenorhabditis elegans (C. elegans). The size of unactivated sperms was deceased by 10 T SMF exposure, instead of the morphology. Exposure to 10 T SMF significantly altered the function of sperms in him-5 worms including the activation of sperms and the non-transferred ratio of sperms. In addition, the brood size assay revealed that 10 T SMF exposure eventually diminished the reproductive capacity of him-5 male worms. The lifespan of outcrossed offspring from exposed him-5 male mutants and unexposed fog-2 female mutants was decreased by 10 T SMF in a time dependent manner. Together, our findings provide novel information regarding the adverse effects of high SMFs on the sperms of C. elegans and their offspring, which can improve our understanding of the fundamental aspects of high SMFs on biological system.
资助项目	Dean's Fund of Hefei Institute of Physical Science[YZJJZX202014] ; National Natural Science Foundation of China[52177227] ; National Natural Science Foundation of China[22006149] ; Anhui Provincial Key Research and Development Programs[202004i07020015] ; Hundred Talents Program[E09BR22]
WOS关键词	FETAL DEVELOPMENT ; DNA-DAMAGE ; C-ELEGANS ; IN-VITRO ; EXPOSURE ; SPERMATOGENESIS ; ORIENTATION ; STRESS ; ACTIVATION ; FERTILITY
WOS研究方向	Environmental Sciences & Ecology ; Toxicology
语种	英语
出版者	ACADEMIC PRESS INC ELSEVIER SCIENCE
WOS记录号	WOS:000832716100002
资助机构	Dean's Fund of Hefei Institute of Physical Science ; National Natural Science Foundation of China ; Anhui Provincial Key Research and Development Programs ; Hundred Talents Program
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/132177]
专题	中国科学院合肥物质科学研究院
通讯作者	Du, Hua; Xu, An
作者单位	1.Chinese Acad Sci, Anhui Prov Key Lab Condensed Matter Phys Extreme, High Magnet Field Lab, Hefei 230031, Anhui, Peoples R China 2.Chinese Acad Sci, Anhui Prov Key Lab Environm Toxicol & Pollut Cont, Hefei Inst Phys Sci, Hefei 230031, Anhui, Peoples R China 3.Chinese Acad Sci, Key Lab High Magnet Field & Ion Beam Phys Biol, Hefei 230031, Anhui, Peoples R China 4.Univ Sci & Technol China, Sch Environm Sci & Optoelect Technol, Hefei 230026, Peoples R China
推荐引用方式 GB/T 7714	Yang, Baolin,Yang, Zhen,Cheng, Lei,et al. Effects of 10 T static magnetic field on the function of sperms and their offspring in Caenorhabditis elegans[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2022,240.
APA	Yang, Baolin.,Yang, Zhen.,Cheng, Lei.,Li, Yang.,Zhou, Tong.,...&Xu, An.(2022).Effects of 10 T static magnetic field on the function of sperms and their offspring in Caenorhabditis elegans.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,240.
MLA	Yang, Baolin,et al."Effects of 10 T static magnetic field on the function of sperms and their offspring in Caenorhabditis elegans".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 240(2022).