Thin membrane-based potentiometric sensors for sensitive detection of polyions

doi:10.1039/d2ay01223e

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	Thin membrane-based potentiometric sensors for sensitive detection of polyions
	Wang, Kaikai 1,2; Liang, Rongning 2; Qin, Wei 2
刊名	ANALYTICAL METHODS
	2022-10-20
卷号	14 期号:40 页码:4008-4013
ISSN号	1759-9660
DOI	10.1039/d2ay01223e
通讯作者	Liang, Rongning(rnliang@yic.ac.cn)
英文摘要	A novel protocol for development of sensitive and rapid polymeric membrane polyion sensitive electrodes has been explored in this work. In contrast to the traditional polyion electrodes which usually have a sensing membrane thickness of 100 similar to 200 mu m, a thin membrane electrode with a membrane thickness of 5 mu m is proposed to detect polyions. By using such thin membrane configuration, the diffusion of polyions from the organic boundary layer into the bulk of the membrane can be effectively blocked. The induced accumulation of polyions in the membrane boundary layer largely enhances the obtained potential response. It has been found that the proposed electrode shows a remarkably improved sensitivity and measurement time over conventional potentiometric polyion sensors based on the thick membranes. By using protamine as a model of polyions, the new concept offers a detection limit nearly two orders of magnitude lower than those obtained by the traditional thick-membrane polyion electrodes for potentiometric measurements of polyions. The proposed polyion sensing platform offers great promise in the sensitive and rapid detection of polyions as well as other polyion-involved bioanalyses.
WOS关键词	ION-SELECTIVE ELECTRODES ; ELECTROCHEMICAL ASSAY ; REVERSIBLE DETECTION ; SOLID-CONTACT ; HEPARIN ; INHIBITORS ; BLOOD
WOS研究方向	Chemistry ; Food Science & Technology ; Spectroscopy
语种	英语
WOS记录号	WOS:000865259500001
资助机构	National Natural Science Foundation of China ; Key Deployment Project of Centre for Ocean Mega-Research of Science, Chinese Academy of Sciences ; Youth Innovation Promotion Association of the Chinese Academy of Sciences ; Taishan Scholar Program of Shandong Province
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/31760]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
通讯作者	Liang, Rongning
作者单位	1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, CAS Key Lab Coastal Environm Proc & Ecol Remediat, YICCAS,Shandong Key Lab Coastal Environm Proc, Yantai 264003, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Wang, Kaikai,Liang, Rongning,Qin, Wei. Thin membrane-based potentiometric sensors for sensitive detection of polyions[J]. ANALYTICAL METHODS,2022,14(40):4008-4013.
APA	Wang, Kaikai,Liang, Rongning,&Qin, Wei.(2022).Thin membrane-based potentiometric sensors for sensitive detection of polyions.ANALYTICAL METHODS,14(40),4008-4013.
MLA	Wang, Kaikai,et al."Thin membrane-based potentiometric sensors for sensitive detection of polyions".ANALYTICAL METHODS 14.40(2022):4008-4013.