Preparation of S-iron-enriched yeast using siderophores and its effect on iron deficiency anemia in rats

doi:10.1016/j.foodchem.2021.130508

	Preparation of S-iron-enriched yeast using siderophores and its effect on iron deficiency anemia in rats
	Zhang, Xin-Guo; Wang, Nan; Ma, Guo-Di; Liu, Zi-Yu; Wei, Guo-Xing; Liu, Wen-Jie
刊名	FOOD CHEMISTRY
	2021-12-15
卷号	365
关键词	Siderophore S-Iron-enriched yeast Iron-deficient anemia Rats
ISSN号	0308-8146
DOI	10.1016/j.foodchem.2021.130508
英文摘要	Efforts to obtain organic trace elements have been made, including yeast enrichment and transformation, but the application of yeast for this purpose is restricted by poor tolerance and low enrichment. Siderophores play an important role in iron transport. Thus, the role of siderophores in iron transport under high-iron conditions and the application of siderophores in the enrichment of elements was explored. The results showed that some siderophores from iron-tolerant strains promoted yeast growth and increased its intracellular iron content. Among them, siderophore TZT-12 (from LK1110) was the best for promoting yeast growth and iron conversion. The siderophore-iron-enriched yeast (S-iron-enriched yeast) effectively restored the iron concentration, and an iron concentration of 59.40 mg/g was obtained by adding TZT-12. Iron deficiency anemia in rats was significantly mitigated with S-iron-enriched yeast compared with ferrous sulfate. These findings provide a new perspective on the preparation of organic trace elements for supplementation or food fortification.
WOS研究方向	Chemistry ; Food Science & Technology ; Nutrition & Dietetics
语种	英语
出版者	ELSEVIER SCI LTD
WOS记录号	WOS:000687708700012
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/148608]
专题	生命科学与工程学院
作者单位	Lanzhou Univ Technol, Sch Life Sci & Engn, Key Lab Herbal Tebitan Drug Screening & Deep Proc, Lanzhou 730050, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Xin-Guo,Wang, Nan,Ma, Guo-Di,et al. Preparation of S-iron-enriched yeast using siderophores and its effect on iron deficiency anemia in rats[J]. FOOD CHEMISTRY,2021,365.
APA	Zhang, Xin-Guo,Wang, Nan,Ma, Guo-Di,Liu, Zi-Yu,Wei, Guo-Xing,&Liu, Wen-Jie.(2021).Preparation of S-iron-enriched yeast using siderophores and its effect on iron deficiency anemia in rats.FOOD CHEMISTRY,365.
MLA	Zhang, Xin-Guo,et al."Preparation of S-iron-enriched yeast using siderophores and its effect on iron deficiency anemia in rats".FOOD CHEMISTRY 365(2021).