Fusiform-like metal-organic framework for enantioselective discrimination of tryptophan enantiomers

doi:10.1016/j.electacta.2022.140409

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	Fusiform-like metal-organic framework for enantioselective discrimination of tryptophan enantiomers
	Li, Hongxia; Wang, Letong; Yan, Simeng; Chen, Jinliang; Zhang, Mengmeng; Zhao, Rui; Niu, Xiaohui; K., Wang
刊名	Electrochimica Acta
	2022-07-01
卷号	419
关键词	Crystalline materials Electrochemical sensors Enantiomers Ligands Medicine Metal ions Metal-Organic Frameworks Metals Organometallics Voltammetry Chiral recognition D-tryptophan Enantioselective discrimination Framework structures L-tryptophan Ligand exchanges Metalorganic frameworks (MOFs) Stereoselective recognition Terephthalic acids Tryptophan enantiomers
ISSN号	0013-4686
DOI	10.1016/j.electacta.2022.140409
英文摘要	Construction of chiral electrochemical sensors for stereoselective recognition is of great significance in medicine and pharmacy. Compared with traditional chiral recognition materials, metal organic frameworks (MOFs) are undoubtedly a new type of materials for chiral recognition. Here, we report a novel MOFs structure (Phe-Cu-PTA) that formed by the metal ion Cu2+ and organic ligands [1.10-Pheanthroline (Phe), Terephthalic acid (PTA)], which was used to distinguish L-tryptophan and D-tryptophan (L/D-Trp) enantiomers. Differential pulse voltammetry (DPV) test results showed the ability of the Phe-Cu-PTA to recognize the Trp-enantiomers. Owing to the different steric configuration of the L/D-Trp-enantiomers, host (MOFs)-guest (Trp-isomers) interactions are different for L/D-Trp, the peak current values of L-Trp-and D-Trp-are obviously different, thereby effectively distinguishing the Trp-isomers. The results demonstrated that the developed MOFs (Phe-Cu-PTA) showed significantly higher binding force toward D-Trp-than L-Trp. Therefore, the proposed electrochemical chiral interface can be considered as a potential platform for enantiomeric recognition of chiral compounds. © 2022 Elsevier Ltd
WOS研究方向	Electrochemistry
语种	英语
出版者	Elsevier Ltd
WOS记录号	WOS:000807364400003
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/158454]
专题	石油化工学院
作者单位	School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou; 730050, China
推荐引用方式 GB/T 7714	Li, Hongxia,Wang, Letong,Yan, Simeng,et al. Fusiform-like metal-organic framework for enantioselective discrimination of tryptophan enantiomers[J]. Electrochimica Acta,2022,419.
APA	Li, Hongxia.,Wang, Letong.,Yan, Simeng.,Chen, Jinliang.,Zhang, Mengmeng.,...&K., Wang.(2022).Fusiform-like metal-organic framework for enantioselective discrimination of tryptophan enantiomers.Electrochimica Acta,419.
MLA	Li, Hongxia,et al."Fusiform-like metal-organic framework for enantioselective discrimination of tryptophan enantiomers".Electrochimica Acta 419(2022).