In order to study the correlation between the internal flow noise of the centrifugal pump and the turbulent pressure pulsation, a single-stage single-suction centrifugal pump was used as the research object by the combination of numerical calculation and experiment. Based on the RNG k-Ε model and the N-S equation, the model pump was simulated numerically by CFD. A dipole sound source was extracted by the turbulent pulse action of the volute wall surface according to the FW-H equation. The acoustic field of the model pump was solved on the basis of the boundary element method, and the sound pressure distribution of the internal flow field under the action of the dipole sound source of the volute wall and the frequency response of the inlet and outlet fields were obtained. The results show that the distribution of hydrodynamic noise inside the centrifugal pump is related to the pressure pulsation, presenting obvious dipole distribution and disturbance at the tongue. The sound pressure value of the field is mainly concentrated in the blade passing frequency and double frequency, in which the blade passing frequency is the strongest, and the sound pressure value decreases obviously under other double frequency. The main frequency of hydrodynamic noise is the blade passing frequency. © 2020, Science Press, Institute of Engineering Thermophysics, CAS and Springer-Verlag GmbH Germany, part of Springer Nature.