Optimizing L-(+)-lactic acid production by thermophile Lactobacillus plantarum As 1 3 using alternative nitrogen sources with response surface method

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	Optimizing L-(+)-lactic acid production by thermophile Lactobacillus plantarum As 1 3 using alternative nitrogen sources with response surface method
	Liu, Binbin 1,2; Yang, Maohua 1,2; Qi, Benkun 1,2; Chen, Xiangrong 1; Su, Zhiguo 1; Wan, Yinhua 1
刊名	BIOCHEMICAL ENGINEERING JOURNAL
	2010-11-15
卷号	52 期号:2-3 页码:212-219
关键词	L-(+)-Lactic acid Thermophile Lactobacillus plantarum As 1 3 Malt sprout Corn steep liquor Response surface methodology Nitrogen source
ISSN号	1369-703X
通讯作者	Wan, YH
英文摘要	The effects of five alternative nitrogen sources namely malt sprout (MS) corn steep liquor (CSL) NH(4)Cl NH(4)NO(3) and diamine citrate (DC) were investigated on the L-(+)-lactic acid (LA) production by thermophile Lactobacillus plantarum As 1 3 Through the statistical analysis of the results by three steps of response surface methodology (RSM) design MS and CSL were found to have significant effects on the LA production and their optimal concentrations in the medium should be 16 0 g/L and 12 0 g/L respectively The verification of the optimized medium showed that the maximum specific growth rate (mu(m)) was 1 09 h(-1) the cell yield coefficient (Y(X/S)) and the L-(+)-lactic acid yield coefficient (Y(P/S)) were 0 233 (OD(620)/g) and 0 98 (g/g) and the maximum volumetric productivity and the average volumetric productivity were 13 0 g/L h and 3 20 g/L h respectively The results indicate that the LA production can also be enhanced with the inexpensive nitrogen source alternatives (C) 2010 Elsevier B V All rights reserved
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Technology
类目[WOS]	Biotechnology & Applied Microbiology ; Engineering, Chemical
研究领域[WOS]	Biotechnology & Applied Microbiology ; Engineering
关键词[WOS]	STEEPEST ASCENT METHOD ; L(+) LACTIC-ACID ; CASEI NRRL B-441 ; MEMBRANE BIOREACTOR ; FACTORIAL DESIGN ; UNSTRUCTURED MODEL ; WHEY PERMEATE ; CHEESE WHEY ; OPTIMIZATION ; FERMENTATION
收录类别	SCI
语种	英语
WOS记录号	WOS:000284571200015
公开日期	2013-11-12
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.ipe.ac.cn/handle/122111/5571]
专题	过程工程研究所_生化工程国家重点实验室
作者单位	1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Liu, Binbin,Yang, Maohua,Qi, Benkun,et al. Optimizing L-(+)-lactic acid production by thermophile Lactobacillus plantarum As 1 3 using alternative nitrogen sources with response surface method[J]. BIOCHEMICAL ENGINEERING JOURNAL,2010,52(2-3):212-219.
APA	Liu, Binbin,Yang, Maohua,Qi, Benkun,Chen, Xiangrong,Su, Zhiguo,&Wan, Yinhua.(2010).Optimizing L-(+)-lactic acid production by thermophile Lactobacillus plantarum As 1 3 using alternative nitrogen sources with response surface method.BIOCHEMICAL ENGINEERING JOURNAL,52(2-3),212-219.
MLA	Liu, Binbin,et al."Optimizing L-(+)-lactic acid production by thermophile Lactobacillus plantarum As 1 3 using alternative nitrogen sources with response surface method".BIOCHEMICAL ENGINEERING JOURNAL 52.2-3(2010):212-219.