On June 17, 2020, a large debris flow occurred in the Meilong catchment following a short-duration, high -intensity rainstorm. The debris flow was initiated by two shallow landsides upstream of the catchment and had a volume of approximately 7.7 x 10(5 )m(3). It blocked the river and then induced flooding, causing significant losses to the local residents. In this study, through a combination of field observation, image interpretation, and laboratory experiments, the initiation mechanism, erosion depth along the main channel, and deposition area of this debris flow were comprehensively analyzed. A sequentially integrated numerical model considering the rainfall interception by vegetation, infiltration, and runoff process was developed. Considering the spatial variations in the climatic, hydrological, and geotechnical parameters, the entire process of debris flow initiation, motion, entrainment, and deposition was simulated. The computational outcomes matched well with the field observation results. A combination of the proposed integrated model and spatially varying parameters can be used to effectively describe the debris flow characteristics in the initiation and propagation stages and provide significant insights into the physical processes involved in such hazards.