Study on quantitative expression of PPAR. and ADRP in muscle and its association with intramuscular fat deposition of pig

doi:10.1186/s40064-016-3187-0

CORC > 植物研究所 > 中国科学院植物研究所 > 中科院北方资源植物重点实验室

	Study on quantitative expression of PPAR. and ADRP in muscle and its association with intramuscular fat deposition of pig
	Cui, Jingxiang 3; Chen, Wei ; Liu, Jie 3; Xu, Tao 2; Zeng, Yongqing
刊名	SPRINGERPLUS
	2016
卷号	5
关键词	Pig PPAR gamma ADRP QRT-PCR Fat deposition
ISSN号	2193-1801
DOI	10.1186/s40064-016-3187-0
文献子类	Article
英文摘要	Background: Intramuscular fat (intramuscular fat, IMF) is one of the important traits of pork quality. How to reasonably improve the intramuscular fat content is the most focus researchers. Some possible regulation of intramuscular fat deposition of candidate genes to cause the attention of people. The objective of this study was to elucidate the relationship between peroxisome proliferator-activated receptor. (PPAR.) and adipose differentiation-related protein (ADRP) mRNA expression and intramuscular fat (IMF) deposition in the muscle tissue of three breeds of pig: Laiwu (LW), Lulai Black (LL), and Large White (LY). Results: qPCR analysis of the PPAR. and ADRP genes in the three breeds of pig revealed PPAR. and ADRP mRNA expression profiles of LW > LL > LY and LL > LW > LY, respectively. PPAR. mRNA expression was significantly and positively correlated with IMF deposition (p < 0.05). There were significant correlations between PPAR. and ADRP mRNA expression levels (p < 0.01). Conclusions: These results suggest correlations between PPAR. and ADRP in fat deposition and regulation in pigs, PPAR. gene may be a main effector of IMF content and play an important role during adipocyte differentiation in pigs, thereby providing new information to further elucidate molecular mechanisms associated with intramuscular fat deposition in Laiwu pigs and provides new data for further molecular studies of mechanisms underlying intramuscular fat deposition in human obesity. The continued elucidation of specific genetic mechanisms between PPAR. and ADRP warrants further studies.
学科主题	Multidisciplinary Sciences
出版地	CHAM
WOS关键词	MOLECULAR CHARACTERIZATION ; PORCINE PREADIPOCYTES ; LONGISSIMUS-DORSI ; GENE-EXPRESSION ; MEAT QUALITY ; GAMMA ; DIFFERENTIATION ; BREEDS ; PCR ; ADIPOPHILIN
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
语种	英语
出版者	SPRINGER INTERNATIONAL PUBLISHING AG
WOS记录号	WOS:000391798600005
资助机构	National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31401055] ; Shandong Province Agricultural Animal Breeding Project of China [2013LZ02-015] ; Shandong Province Modern Pig Technology and Industry System Project [SDAIT-06-022-03] ; Shandong Province Weifang city science and Technology Bureau Project of China [201301153] ; Shandong University of science and technology project [J16LE58]
内容类型	期刊论文
源URL	[http://ir.ibcas.ac.cn/handle/2S10CLM1/25256]
专题	中科院北方资源植物重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, Key Lab Plant Resources, Beijing 100093, Peoples R China 2.Weifang Univ Sci & Technol, Shouguang 262700, Shandong, Peoples R China 3.Shandong Agr Univ, Coll Anim Sci & Technol, Tai An 271018, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Cui, Jingxiang,Chen, Wei,Liu, Jie,et al. Study on quantitative expression of PPAR. and ADRP in muscle and its association with intramuscular fat deposition of pig[J]. SPRINGERPLUS,2016,5.
APA	Cui, Jingxiang,Chen, Wei,Liu, Jie,Xu, Tao,&Zeng, Yongqing.(2016).Study on quantitative expression of PPAR. and ADRP in muscle and its association with intramuscular fat deposition of pig.SPRINGERPLUS,5.
MLA	Cui, Jingxiang,et al."Study on quantitative expression of PPAR. and ADRP in muscle and its association with intramuscular fat deposition of pig".SPRINGERPLUS 5(2016).