The ferroelectric materials own the natural anti-irradiation property, paving great potentials and applications regarding the aerospace fields. Benefiting from this property, LiNbO3-based surface acoustic wave (SAW) devices can be used for high accuracy sensing signal test under extreme circumstances. In this work, the 128 degrees YX cut LiNbO3 substrate was adopted for SAW resonator temperature sensor application, and the response frequency varied from 180.44 MHz to 177.628 MHz with temperature from 21.9 degrees C to 199.9 degrees C. Subsequently, the device irradiated by 100 Krad Gamma ray was tested with vector network analyzer (VNA). A maximum frequency shift of similar to 0.38% was found under gamma-ray irradiation with a dose of 100 Krad on account of slight irradiation effect. The results verify the radiation resistance ability of SAW for development of highly reliable temperature sensor in the irradiation environment.