Developing high-performance polymeric tribo-materials with superior integrated properties is of vital importance in consideration of energy and environment. In this work, using commercial epoxy (EP) as matrix, the hybrids constructed by graphene oxide (GO) and tungsten disulfide (WS₂) were successfully synthesized by hydrothermal reaction to enhance properties of EP composites. The WS₂ nano-flowers were uniformly grown onto the surface of GO nanosheets, which interconnected with each other to develop a hierarchical structure. The unique hierarchical microstructure of WS₂@GO nanohybrids with large specific surface area and abundant active groups was conducive to the filler-polymer interfacial interactions and multiple enhancement. As a result, the resultant EP/WS₂@GO composites displayed outstanding integrated properties, including 81.7% higher tensile strength, 13 °C higher thermal stability, 47.04% lower friction coefficient, and 36.57% higher abrasion resistance. This work will provide a significant guidance for the development of high-performance polymeric tribo-materials.