Due to the improvement of the quality of industrial products, zero-failure data often occurs during the reliability life test or in the service environment, and such problems cannot be handled using traditional reliability estimation methods. Regarding the processing and analysis of zero-failure data, the confidence limit assessment methods were proposed by some researchers. Based on the existing research, a confidence limit method set (CLMS) is established in the Weibull distribution for reliability estimation of zero-failure data. The method set includes the unilateral confidence limit method and optimal confidence limit method, so that almost all existing grouping types of zero-failure data can be quickly evaluated, and multiple methods can be used in parallel to deal with the same problem. The effectiveness and high efficiency of the CLMS combined with numerical simulation examples have been verified, and the possibility of analyzing multiple groups of zero-failure data with a confidence limit method suitable for processing single group of zero-failure data is expanded. Finally, the actual effect of the method set is verified by the single group of zero-failure data of rolling bearings and the multiple groups of zero-failure data of torque motors. The results of the example evaluation show that the CLMS has obvious advantages in practical engineering applications.