Patterned diphenylalanine nanotubes regulate the behavior of hippocampal neurons.

CORC > 沈阳自动化研究所 > 中国科学院沈阳自动化研究所 > 机器人学研究室

	Patterned diphenylalanine nanotubes regulate the behavior of hippocampal neurons.
	Zu LP(祖立鹏); Shi HY(石慧瑶); Yang J(杨佳); Fu, Yuanyuan ; Wang WX(王文学); Liu LQ(刘连庆)
	2021
会议日期	August 2-6,. 2021
会议地点	Xi'an, China
关键词	diphenylalanine self-assembled hippocampal neurons nanotubes neural network
页码	413-416
英文摘要	The establishment of functional neural networks has been extensively studied in vitro. Various patterned substrates based on micro-nano processing and fabrication technology are used to control the connection mode of neurons. In this study, unidirectional arranged and radial arranged diphenylalanine (FF) nanotubes are made for the cultivation of hippocampal neurons. The two different FF nanotubes patterned substrates produced in this article induced two different behaviors of hippocampal neurons. Directional arranged FF nanotubes can induce the directional arrangement of neurons. The directionality of neurons can be maintained even after FF is dissolved. On the other hand, neurons quickly migrated into clusters under the induction of radial FF nanotubes and further form a complex patterned connection network. The method proposed in this paper can be used to study various behaviors of neurons, and further can be used to study the different patterned structures to construct different neural network types.
产权排序	1
会议录	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale
会议录出版者	IEEE
会议录出版地	New York
语种	英语
ISSN号	2694-510X
ISBN号	978-1-6654-4881-9
WOS记录号	WOS:000790200900091
内容类型	会议论文
源URL	[http://ir.sia.cn/handle/173321/30217]
专题	沈阳自动化研究所_机器人学研究室
通讯作者	Wang WX(王文学); Liu LQ(刘连庆)
作者单位	1.University of Chinese Academy of Sciences, Beijing, China 2.The State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China 3.Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang, China 4.The Department of Histology and Embryology, Basic Medical College, China Medical University, Shenyang, China
推荐引用方式 GB/T 7714	Zu LP,Shi HY,Yang J,et al. Patterned diphenylalanine nanotubes regulate the behavior of hippocampal neurons.[C]. 见:. Xi'an, China. August 2-6,. 2021.