Cell culturing in electropolymerized hydrogel multi-layer nets fabricated in an electrokinetics microfluidic chip

CORC > 沈阳自动化研究所 > 中国科学院沈阳自动化研究所 > 机器人学研究室

	Cell culturing in electropolymerized hydrogel multi-layer nets fabricated in an electrokinetics microfluidic chip
	Li P(李盼)1,2; Liu LQ(刘连庆)2; Zhang YZ(章昱昭)1,2; Yu HB(于海波)2; Lee, Gwo-Bin 4; Wang YC(王越超)2; Li WJ(李文荣)3
	2018
会议日期	November 11-15, 2018
会议地点	Kaohsiung, Taiwan
关键词	3D cell culture 3D hydrogel Bio-fabrication Optically-induced electrokinetics
页码	252-255
英文摘要	Three-dimensional (3D) micro-engineered hydrogel biomaterials incorporating cells is a promising in vitro bio-model for tissue engineering. We report a visible-light induced layer-by-layer microfabrication method for large scale tunable 3D hydrogel network and its application in 3D cell culturing and modulation. This optically induced electropolymerization method was previously reported for two-dimensional (2D) hydrogel patterning and cell patterning. Here, we improved the fabrication process by designing a series of switching "digitally-controlled photomasks" to continuously fabricate multi-layered 3D net-like hydrogel scaffolds with tunable pores and gaps. Cell spreading and migrating behaviors were further investigated after incorporating them into this biocompatible hydrogel scaffold. This method may shine some light on the in vitro reconstruction of physiologically related bio-microenvironments.
源文献作者	ASE Group ; et al. ; Industrial Technology Research Institute (ITRI) ; KLOE ; QuantaMatrix, Inc. ; Zeon Corporation
产权排序	1
会议录	22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
会议录出版者	Chemical and Biological Microsystems Society
会议录出版地	San Diego, CA, USA
语种	英语
ISBN号	978-1-5108-9757-1
内容类型	会议论文
源URL	[http://ir.sia.cn/handle/173321/26356]
专题	沈阳自动化研究所_机器人学研究室
通讯作者	Li WJ(李文荣)
作者单位	1.University of the Chinese Academy of Sciences, Beijing 100049, China 2.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences (CAS), Shenyang 110016, China 3.Department of Mechanical Engineering, City University of Hong Kong, Kowloon, Hong Kong 4.Department of Power Mechanical Engineering, National Tsinghua University, Hsinchu 300, Taiwan
推荐引用方式 GB/T 7714	Li P,Liu LQ,Zhang YZ,et al. Cell culturing in electropolymerized hydrogel multi-layer nets fabricated in an electrokinetics microfluidic chip[C]. 见:. Kaohsiung, Taiwan. November 11-15, 2018.