Enzyme membrane reactors for production of oligosaccharides: A review on the interdependence between enzyme reaction and membrane separation

doi:10.1016/j.seppur.2020.116840

	Enzyme membrane reactors for production of oligosaccharides: A review on the interdependence between enzyme reaction and membrane separation
	Su, Ziran 1; Luo, Jianquan 2; Li, Xianhui 1; Pinelo, Manuel 1
刊名	SEPARATION AND PURIFICATION TECHNOLOGY
	2020-07-15
卷号	243 页码:17
关键词	Oligosaccharides Enzymatic membrane reactor Molecular weight control Membrane fouling
ISSN号	1383-5866
DOI	10.1016/j.seppur.2020.116840
英文摘要	Certain types of oligosaccharides are especially interesting due to their high commercial value, however, the traditional oligosaccharide fabrication process is neither sustainable nor tailorable for obtainment of commercial standard oligosaccharide streams. The use of enzymatic membrane reactors (EMR) is proposed as a sustainable strategy to obtain oligosaccharides through a coupled bioreaction-separation process. In such process, glycosidic enzymes function as catalysts and membranes as selective barriers tailoring the molecular weight of products. Most of previous studies on oligosaccharides production by EMR have focused either on optimal operation of the enzyme reaction or the membrane filtration separately, but none of them have considered the implications of coupling both steps together. It is therefore the aim of this review to critically assess the available literature on the topic from a novel point of view: by paying special attention to the interactions between enzyme reaction-membrane filtration, which are critical for the performance of the overall process. Depending on the reaction conditions, the generated fouling directly affecting filtration performance varies. Such fouling depends on the membrane type and operation mode, which will in turn have an influence on the enzyme performance. The proposed review aims at providing a critical overview of the variables influencing performance and will provide tips for optimal configuration and operation of the coupled system.
资助项目	Chinese Scholarship Council[201804910747] ; Villum Foundation (Villum Experiment grant)[00028005]
WOS关键词	MOLECULAR-WEIGHT ; CHITOSAN OLIGOSACCHARIDES ; GALACTO-OLIGOSACCHARIDES ; PECTIC-OLIGOSACCHARIDES ; ULTRAFILTRATION MEMBRANES ; HEPARIN OLIGOSACCHARIDES ; DIFFERENT CONFIGURATIONS ; FRUCTO-OLIGOSACCHARIDES ; PROCESS INTENSIFICATION ; TRANSMEMBRANE PRESSURE
WOS研究方向	Engineering
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000528197800003
资助机构	Chinese Scholarship Council ; Villum Foundation (Villum Experiment grant)
内容类型	期刊论文
源URL	[http://ir.ipe.ac.cn/handle/122111/40304]
专题	中国科学院过程工程研究所
通讯作者	Luo, Jianquan; Pinelo, Manuel
作者单位	1.Tech Univ Denmark, Proc & Syst Engn Ctr, Dept Chem & Biochem Engn, DK-2800 Lyngby, Denmark 2.Chinese Acad Sci, Univ Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Su, Ziran,Luo, Jianquan,Li, Xianhui,et al. Enzyme membrane reactors for production of oligosaccharides: A review on the interdependence between enzyme reaction and membrane separation[J]. SEPARATION AND PURIFICATION TECHNOLOGY,2020,243:17.
APA	Su, Ziran,Luo, Jianquan,Li, Xianhui,&Pinelo, Manuel.(2020).Enzyme membrane reactors for production of oligosaccharides: A review on the interdependence between enzyme reaction and membrane separation.SEPARATION AND PURIFICATION TECHNOLOGY,243,17.
MLA	Su, Ziran,et al."Enzyme membrane reactors for production of oligosaccharides: A review on the interdependence between enzyme reaction and membrane separation".SEPARATION AND PURIFICATION TECHNOLOGY 243(2020):17.