Sulfoximines Assisted Rh(III)-Catalyzed C-H Activation/Annulation Cascade to Synthesize Highly Fused Indeno-1,2-benzothiazines

doi:10.1021/acs.joc.1c01820

	Sulfoximines Assisted Rh(III)-Catalyzed C-H Activation/Annulation Cascade to Synthesize Highly Fused Indeno-1,2-benzothiazines
	Li, Jian 1,2; Li, Hui 1,2; Fang, Daqing 2; Liu, Lingjun 2; Han, Xu 2; Sun, Jina 2,3; Li, Chunpu 2; Zhou, Yu 2,3; Ye, Deju 4; Liu, Hong 1,2,3
刊名	JOURNAL OF ORGANIC CHEMISTRY
	2021-11-05
卷号	86 期号:21 页码:15217-15227
ISSN号	0022-3263
DOI	10.1021/acs.joc.1c01820
通讯作者	Ye, Deju(dejuye@nju.edu.cn) ; Liu, Hong(hliu@simm.ac.cn)
英文摘要	A facile access to highly fused tetracyclic indeno-1,2-benzothiazines has been established via a Rh(III)-catalyzed C-H bond activation and intramolecular annulation cascade between sulfoximides and all-carbon diazo indandiones. This strategy is characterized by the fact that the diazo coupling partners do not require preactivation, along with its high efficiency, broad substrate generality, and facile transformation. Particularly, the highly conjugated tetracyclic products demonstrate good optical properties and can easily enter cells to emit bright fluorescence for live cell imaging.
资助项目	National Natural Science Foundation of China[21632008] ; National Natural Science Foundation of China[21877118] ; National Natural Science Foundation of China[81620108027] ; National Natural Science Foundation of China[91953108] ; Science Technology Commission of Shanghai Municipality[18JC1411304] ; Science Technology Commission of Shanghai Municipality[18431907100] ; SASIBS Scholarship Program ; Youth Innovation Promotion Association CAS
WOS关键词	CATALYZED OXIDATIVE ANNULATION ; DIAZO-COMPOUNDS ; BOND FORMATION ; CARBENOID FUNCTIONALIZATION ; ACTIVATION ; ACCESS ; 1,2-BENZOTHIAZINES ; BENZOTHIAZINES ; BENZYLAMINES ; DERIVATIVES
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000716778300076
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/299042]
专题	中国科学院上海药物研究所
通讯作者	Ye, Deju; Liu, Hong
作者单位	1.Nanjing Univ Chinese Med, Sch Chinese Mat Med, Nanjing 210023, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Analyt Chem Life Sci, Nanjing 210023, Peoples R China
推荐引用方式 GB/T 7714	Li, Jian,Li, Hui,Fang, Daqing,et al. Sulfoximines Assisted Rh(III)-Catalyzed C-H Activation/Annulation Cascade to Synthesize Highly Fused Indeno-1,2-benzothiazines[J]. JOURNAL OF ORGANIC CHEMISTRY,2021,86(21):15217-15227.
APA	Li, Jian.,Li, Hui.,Fang, Daqing.,Liu, Lingjun.,Han, Xu.,...&Liu, Hong.(2021).Sulfoximines Assisted Rh(III)-Catalyzed C-H Activation/Annulation Cascade to Synthesize Highly Fused Indeno-1,2-benzothiazines.JOURNAL OF ORGANIC CHEMISTRY,86(21),15217-15227.
MLA	Li, Jian,et al."Sulfoximines Assisted Rh(III)-Catalyzed C-H Activation/Annulation Cascade to Synthesize Highly Fused Indeno-1,2-benzothiazines".JOURNAL OF ORGANIC CHEMISTRY 86.21(2021):15217-15227.