Neural Mechanisms of Prospection in Individuals With Schizotypal Traits, Autistic Traits, or Depressive Symptoms | |
Zhang, Rui-ting2,4; Yang, Zhuo-ya2,4; Huang, Jia2,4; Wang, Yong-ming2,3,4; Zhou, Han-yu2,4; Wang, Yi2,4; Lui, Simon S. Y.1,5; Cheung, Eric F. C.1; Chan, Raymond C. K.2,3,4 | |
刊名 | JOURNAL OF ABNORMAL PSYCHOLOGY |
2021-11-01 | |
通讯作者邮箱 | rckchan@psych.ac.cn (r.c.k. chan) |
卷号 | 130期号:8页码:807-814 |
关键词 | prospection schizotypal traits autistic traits depressive symptoms default model network |
ISSN号 | 0021-843X |
DOI | 10.1037/abn0000709 |
产权排序 | 1 |
文献子类 | 实证研究 |
英文摘要 | General Scientific Summary This study provided preliminary findings showing that individuals with autistic traits and individuals with schizotypal traits may exhibit subtle neural alterations during prospection albeit their intact behavioral performance on prospection. Altered neural responses in the anterior cingulate cortex and frontal gyrus in individuals with autistic traits may indicate that a subtle neural changes for imagining future scenarios and events, while the altered neural responses in caudate in individuals with schizotypal traits may indicate a compensated neural changes for processing positive emotions during prospection. Prospection refers to the ability to mentally construct future events, which is closely related to motivation and anhedonia. The neural underpinning of impaired prospection in psychiatric populations remains unclear. We recruited 34 individuals with autistic traits (AT), 27 individuals with schizotypal traits (ST), 31 individuals with depressive symptoms (DS), and 35 controls. Participants completed a prospection task while undergoing functional Magnetic Resonance Imaging (MRI). We found that regions of the "default mode network" including the medial frontal gyrus, the posterior cingulate cortex, the precuneus and the parahippocampus were activated; and regions of the "task-positive network" including the inferior parietal lobe, the inferior frontal gyrus and the precentral gyrus were deactivated during prospection in controls. Compared with controls, AT, ST, and DS showed comparable behavioral performance on prospection. However, reduced activation in anterior cingulate cortex and frontal gyrus was found in AT individuals relative to controls during prospection. ST individuals showed hyperactivation in the caudate relative to controls when processing positive emotion, while DS individuals and controls showed similar neural responses during prospection. |
收录类别 | SCI |
资助项目 | National Key Research and Development Program[2016YFC0906402] ; National Science Fund China[81571317] ; Beijing Municipal Science & Technology Commission[Z161100000216138] ; Beijing Training Project for the Leading Talents in Science and Technology[Z15110000031 5020] ; Chinese Academy of Sciences (CAS) Key Laboratory of Mental Health, Institute of Psychology |
WOS关键词 | EPISODIC FUTURE THINKING ; CORE NETWORK ; MEMORY ; PLEASURE ; VALIDITY ; DEFICITS ; VERSION ; BRAIN ; SCALE ; PHQ-9 |
WOS研究方向 | Psychology ; Psychiatry |
语种 | 英语 |
出版者 | AMER PSYCHOLOGICAL ASSOC |
WOS记录号 | WOS:000724046500001 |
资助机构 | National Key Research and Development Program ; National Science Fund China ; Beijing Municipal Science & Technology Commission ; Beijing Training Project for the Leading Talents in Science and Technology ; Chinese Academy of Sciences (CAS) Key Laboratory of Mental Health, Institute of Psychology |
内容类型 | 期刊论文 |
源URL | [http://ir.psych.ac.cn/handle/311026/41250] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Chan, Raymond C. K. |
作者单位 | 1.Castle Peak Hosp, Hong Kong, Peoples R China 2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 3.Univ Chinese Acad Sci, Sino Danish Coll, Beijing, Peoples R China 4.Chinese Acad Sci, Chinese Acad Sci CAS Key Lab Mental Hlth, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, 16 Lincui Rd, Beijing 100101, Peoples R China 5.Univ Hong Kong, Dept Psychiat, Hong Kong, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Rui-ting,Yang, Zhuo-ya,Huang, Jia,et al. Neural Mechanisms of Prospection in Individuals With Schizotypal Traits, Autistic Traits, or Depressive Symptoms[J]. JOURNAL OF ABNORMAL PSYCHOLOGY,2021,130(8):807-814. |
APA | Zhang, Rui-ting.,Yang, Zhuo-ya.,Huang, Jia.,Wang, Yong-ming.,Zhou, Han-yu.,...&Chan, Raymond C. K..(2021).Neural Mechanisms of Prospection in Individuals With Schizotypal Traits, Autistic Traits, or Depressive Symptoms.JOURNAL OF ABNORMAL PSYCHOLOGY,130(8),807-814. |
MLA | Zhang, Rui-ting,et al."Neural Mechanisms of Prospection in Individuals With Schizotypal Traits, Autistic Traits, or Depressive Symptoms".JOURNAL OF ABNORMAL PSYCHOLOGY 130.8(2021):807-814. |
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