A Mechanical Device to Evaluate the Effects of Dynamic Loading in Weak-acid Medium on the Bioapatite of Devitalized Cortical Bone

doi:10.1007/s40799-020-00380-x

	A Mechanical Device to Evaluate the Effects of Dynamic Loading in Weak-acid Medium on the Bioapatite of Devitalized Cortical Bone
	Zhovner, M.3; Kalinkevich, A. N.3; Danilchenko, S. N.3; Kuznetsov, V. N.3; Wang, J.1,2; Li, H.1,2; He, J.1,2; Feng, X.1,2
刊名	EXPERIMENTAL TECHNIQUES
	2020-05-27
页码	6
关键词	Bone-loading device Weak-acid medium Bioapatite Calcium elimination Lattice microstrain
ISSN号	0732-8818
DOI	10.1007/s40799-020-00380-x
通讯作者	Kalinkevich, A. N.(kalinkevich@gmail.com)
英文摘要	A new device that enables the application of controlled mechanical loads to devitalized cortical bone blocks in liquid media mimicking physiological environment is described. In the setup, it is possible to evaluate elimination of calcium from a bone during the exposure to slightly acidic media in the presence or absence of periodic controlled mechanical load. In the test experiments with the fragments of cortical bone, the level of calcium elimination from a bone during the experiment has shown the visible dissimilarity for the loaded bone and the unloaded one. The structural alterations in the apatite of the bone after the experiments in the setup have been studied by X-ray diffraction (XRD), which has shown that the lattice microstrain parameter of the bone mineral noticeably increases in the loaded bone compared with unloaded, while the crystallite size shows only a trend to slight increasing. This simple and easy to reproduce bone-loading setup could be used for in vitro studies of the bone material stability under mechanical loading.
资助项目	International Science & Technology Cooperation Program of China[2015DFR30940] ; Science and Technology Research Project of Gansu Province[17JR5RA307] ; Science and Technology Research Project of Gansu Province[145RTSA012] ; Chinese Academy of Science ; Introduced Intelligence project from the State Administration of Foreign Experts Affairs P.R. China (2016)
WOS关键词	X-RAY-DIFFRACTION ; CRYSTALLITE SIZE ; APATITE ; ORGANIZATION ; STIMULATION ; RESORPTION
WOS研究方向	Engineering ; Mechanics ; Materials Science
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000558835200003
资助机构	International Science & Technology Cooperation Program of China ; Science and Technology Research Project of Gansu Province ; Chinese Academy of Science ; Introduced Intelligence project from the State Administration of Foreign Experts Affairs P.R. China (2016)
内容类型	期刊论文
源URL	[http://119.78.100.186/handle/113462/140170]
专题	中国科学院近代物理研究所
通讯作者	Kalinkevich, A. N.
作者单位	1.Key Lab Space Radiobiol Gansu Prov, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Key Lab Heavy Ion Radiat Biol & Med, Inst Modern Phys, Lanzhou 730000, Peoples R China 3.NAS Ukraine, Inst Appl Phys, UA-40000 Sumy, Ukraine
推荐引用方式 GB/T 7714	Zhovner, M.,Kalinkevich, A. N.,Danilchenko, S. N.,et al. A Mechanical Device to Evaluate the Effects of Dynamic Loading in Weak-acid Medium on the Bioapatite of Devitalized Cortical Bone[J]. EXPERIMENTAL TECHNIQUES,2020:6.
APA	Zhovner, M..,Kalinkevich, A. N..,Danilchenko, S. N..,Kuznetsov, V. N..,Wang, J..,...&Feng, X..(2020).A Mechanical Device to Evaluate the Effects of Dynamic Loading in Weak-acid Medium on the Bioapatite of Devitalized Cortical Bone.EXPERIMENTAL TECHNIQUES,6.
MLA	Zhovner, M.,et al."A Mechanical Device to Evaluate the Effects of Dynamic Loading in Weak-acid Medium on the Bioapatite of Devitalized Cortical Bone".EXPERIMENTAL TECHNIQUES (2020):6.