Arabidopsis SUMO protease ASP1 positively regulates flowering time partially through regulating FLC stability

doi:10.1038/cr.2017.102

CORC > 植物研究所 > 中国科学院植物研究所 > 中科院植物分子生理学重点实验室

	Arabidopsis SUMO protease ASP1 positively regulates flowering time partially through regulating FLC stability
	Kong, Xiangxiong ; Luo, Xi ; Qu, Gao-Ping ; Liu, Peng 1; Jin, Jing Bo
刊名	JOURNAL OF INTEGRATIVE PLANT BIOLOGY
	2017
卷号	59 期号:1 页码:15-29
ISSN号	1672-9072
DOI	10.1038/cr.2017.102
文献子类	Article
英文摘要	The initiation of flowering is tightly regulated by the endogenous and environment signals, which is crucial for the reproductive success of flowering plants. It is well known that autonomous and vernalization pathways repress transcription of FLOWERING LOCUS C (FLC), a focal floral repressor, but how its protein stability is regulated remains largely unknown. Here, we found that mutations in a novel Arabidopsis SUMO protease 1 (ASP1) resulted in a strong late-flowering phenotype under long-days, but to a lesser extent under short-days. ASP1 localizes in the nucleus and exhibited a SUMO protease activity in vitro and in vivo. The conserved Cys-577 in ASP1 is critical for its enzymatic activity, as well as its physiological function in the regulation of flowering time. Genetic and gene expression analyses demonstrated that ASP1 promotes transcription of positive regulators of flowering, such as FT, SOC1 and FD, and may function in both CO-dependent photoperiod pathway and FLC-dependent pathways. Although the transcription level of FLC was not affected in the loss-of-function asp1 mutant, the protein stability of FLC was increased in the asp1 mutant. Taken together, this study identified a novel bona fide SUMO protease, ASP1, which positively regulates transition to flowering at least partly by repressing FLC protein stability.
学科主题	Cell Biology
电子版国际标准刊号	1744-7909
出版地	HOBOKEN
WOS关键词	MODIFIER SUMO ; STRESS RESPONSES ; E3 LIGASE ; DEVELOPMENTAL TRANSITIONS ; OVERLY TOLERANT ; UBIQUITIN ; CONJUGATION ; THALIANA ; PLANTS ; ACCUMULATION
语种	英语
出版者	WILEY
WOS记录号	WOS:000408916300008
资助机构	National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31301166, 31471363] ; Ministry of Science and Technology of the People's Republic of ChinaMinistry of Science and Technology, China [2012CB114302] ; Chinese Academy of SciencesChinese Academy of Sciences [XDA08010105]
内容类型	期刊论文
源URL	[http://ir.ibcas.ac.cn/handle/2S10CLM1/22033]
专题	中科院植物分子生理学重点实验室
作者单位	1.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 2.King Abdullah Univ Sci & Technol, Div Biol Environm Sci & Engn, Thuwal, Saudi Arabia 3.Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China
推荐引用方式 GB/T 7714	Kong, Xiangxiong,Luo, Xi,Qu, Gao-Ping,et al. Arabidopsis SUMO protease ASP1 positively regulates flowering time partially through regulating FLC stability[J]. JOURNAL OF INTEGRATIVE PLANT BIOLOGY,2017,59(1):15-29.
APA	Kong, Xiangxiong,Luo, Xi,Qu, Gao-Ping,Liu, Peng,&Jin, Jing Bo.(2017).Arabidopsis SUMO protease ASP1 positively regulates flowering time partially through regulating FLC stability.JOURNAL OF INTEGRATIVE PLANT BIOLOGY,59(1),15-29.
MLA	Kong, Xiangxiong,et al."Arabidopsis SUMO protease ASP1 positively regulates flowering time partially through regulating FLC stability".JOURNAL OF INTEGRATIVE PLANT BIOLOGY 59.1(2017):15-29.