Highlights to phytosterols accumulation and equilibrium in plants: Biosynthetic pathway and feedback regulation

doi:10.1016/j.plaphy.2020.08.021

CORC > 植物研究所 > 中国科学院植物研究所 > 中科院植物分子生理学重点实验室

	Highlights to phytosterols accumulation and equilibrium in plants: Biosynthetic pathway and feedback regulation
	Zhang, Xuan 1; Lin, Kangqi 1; Li, Yinxin
刊名	PLANT PHYSIOLOGY AND BIOCHEMISTRY
	2020
卷号	155 页码:637-649
关键词	Phytosterols biosynthesis Phytosterols conversion Sterol equilibrium Feedback regulation Plasma membrane remodeling
ISSN号	0981-9428
DOI	10.1016/j.plaphy.2020.08.021
文献子类	Review
英文摘要	Phytosterols are a group of sterols exclusive to plants and fungi, but are indispensable to humans because of their medicinal and nutritional values. However, current raw materials used for phytosterols extraction add to the cost and waste in the process. For higher sterols production, major attention is drawn to plant materials abundant in phytosterols and genetic modification. To provide an insight into phytosterols metabolism, the research progress on key enzymes involved in phytosterols biosynthesis and conversions were summarized. CAS, SSR2, SMT, DWFI and CYP710A, the enzymes participating in the biosynthetic pathway, and PSAT, ASAT and SGT, the enzymes involved in the conversion of free sterols to conjugated ones, were reviewed. Specifically, SMT and CYP710A were emphasized for their function on modulating the percentage composition of different kinds of phytosterols. The thresholds of sterol equilibrium and the resultant phytosterols accumulation, which vary in plant species and contribute to plasma membrane remodeling under stresses, were also discussed. By retrospective analysis of the previous researches, we proposed a feedback mechanism regulating sterol equilibrium underlying sterols metabolism. From a strategic perspective, we regard salt tolerant plant as an alternative to present raw materials, which will attain higher phytosterols production in combination with gene-modification.
学科主题	Plant Sciences
出版地	ISSY-LES-MOULINEAUX
WOS关键词	MEMBRANE LIPID-COMPOSITION ; STEROL C-22 DESATURASE ; PLASMA-MEMBRANE ; ARABIDOPSIS-THALIANA ; CYCLOARTENOL SYNTHASE ; FUNCTIONAL-ANALYSIS ; EMBRYO DEVELOPMENT ; MOLECULAR-CLONING ; ESTER SYNTHESIS ; CELL VIABILITY
WOS研究方向	Plant Sciences
语种	英语
出版者	ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
WOS记录号	WOS:000581918000062
资助机构	Strategic Priority Research Program of Chinese Academy of SciencesChinese Academy of Sciences [XDA24010306] ; Chinese Ministry of AgricultureMinistry of Agriculture, China [2016ZX08009-003-002] ; Major Science and Technology Innovation Project of Shandong Province [2019JZZY010726]
内容类型	期刊论文
源URL	[http://ir.ibcas.ac.cn/handle/2S10CLM1/21543]
专题	中科院植物分子生理学重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Xuan,Lin, Kangqi,Li, Yinxin. Highlights to phytosterols accumulation and equilibrium in plants: Biosynthetic pathway and feedback regulation[J]. PLANT PHYSIOLOGY AND BIOCHEMISTRY,2020,155:637-649.
APA	Zhang, Xuan,Lin, Kangqi,&Li, Yinxin.(2020).Highlights to phytosterols accumulation and equilibrium in plants: Biosynthetic pathway and feedback regulation.PLANT PHYSIOLOGY AND BIOCHEMISTRY,155,637-649.
MLA	Zhang, Xuan,et al."Highlights to phytosterols accumulation and equilibrium in plants: Biosynthetic pathway and feedback regulation".PLANT PHYSIOLOGY AND BIOCHEMISTRY 155(2020):637-649.