VARIABILITY OF THE ARBUTIN CONTENT IN WILD GROWING POPULATIONS OF ARCTOSTAPHYLOS UVA-URSI (L.) SPRENG FROM KORAB MOUNTAIN, WESTERN BALKAN

doi:10.20450/mjcce.2021.2095

	VARIABILITY OF THE ARBUTIN CONTENT IN WILD GROWING POPULATIONS OF ARCTOSTAPHYLOS UVA-URSI (L.) SPRENG FROM KORAB MOUNTAIN, WESTERN BALKAN
	Stefkov, G.1; Karanfilova, I. Cvetkovikj 2; Labroska, V 3,4,5; Krsteska, O.1; Qazimi, B.6; Karapandzova, M.1; Gjoni, Z.7; Bardhi, N.8; Kulevanova, S.1
刊名	MACEDONIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING
	2021
卷号	40 期号:1 页码:69-74
关键词	arbutin HPLC bearberry technical maturity R. N. Macedonia R. Albania
ISSN号	1857-5552
DOI	10.20450/mjcce.2021.2095
通讯作者	Stefkov, G.(gstefkov@yahoo.com)
英文摘要	Due to the presence of arbutin and hydroquinone in the bearberry plant (Arctostaphylos uva-ursi (L.) Spreng., Ericaceae), it is widely used as a urinary tract antiseptic and diuretic. The herbal substance consists of whole or cut dried leaves, and it should not contain less than 7.00 % of anhydrous arbutin (Ph.Eur.10). The supply of this herbal substance in Balkan countries mainly comes from a wild plant harvested in the mountains. It is a common practice to collect the leaves during the flowering season of the plant (June-July). There is an abundance of wild growing natural populations of bearberry on Korab Mountain that represents a unique natural resource of this herbal substance for both countries, Albania and N. Macedonia. The aim of the present study was to determine the arbutin content and to assess its variability in the bearberry leaves of seven wild populations from Korab Mountain. The leaves were collected monthly (May-October) during a period of 3 years (2014-2016). The HPLC assay (Ph.Eur.10) revealed that all populations have arbutin content over 7.00 % (7.03-9.42 %) and that the highest content of arbutin can be attained in September/October, during the phase after the fructification. Statistical analysis showed that there is significant difference between the content of arbutin in the different populations. The content was related to the altitude of the collection site and the collection month and year.
WOS关键词	QUANTITATIVE-ANALYSIS ; LEAVES
WOS研究方向	Chemistry ; Engineering
语种	英语
出版者	SOC CHEMISTS TECHNOLOGISTS MADECONIA
WOS记录号	WOS:000681515600008
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/298159]
专题	中国科学院上海药物研究所
通讯作者	Stefkov, G.
作者单位	1.Ss Cyril & Methodius Univ, Fac Pharm, Inst Pharmacognosy, Skopje, North Macedonia 2.Ss Cyril & Methodius Univ, Fac Pharm, Ctr Nat Prod, Skopje, North Macedonia 3.Chinese Acad Sci, Natl Ctr Drug Screening, Shanghai Inst Meteria Med, Shanghai 201203, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Meteria Med, CAS Key Lab Receptor Res, Shanghai 201203, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 6.UBT Higher Educ Inst, Fac Pharm, Prishtina, Kosovo 7.Univ Durres, Durres, Albania 8.Agr Univ, Fac Agr & Environm, Dept Crop Prod, Tirana, Albania
推荐引用方式 GB/T 7714	Stefkov, G.,Karanfilova, I. Cvetkovikj,Labroska, V,et al. VARIABILITY OF THE ARBUTIN CONTENT IN WILD GROWING POPULATIONS OF ARCTOSTAPHYLOS UVA-URSI (L.) SPRENG FROM KORAB MOUNTAIN, WESTERN BALKAN[J]. MACEDONIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING,2021,40(1):69-74.
APA	Stefkov, G..,Karanfilova, I. Cvetkovikj.,Labroska, V.,Krsteska, O..,Qazimi, B..,...&Kulevanova, S..(2021).VARIABILITY OF THE ARBUTIN CONTENT IN WILD GROWING POPULATIONS OF ARCTOSTAPHYLOS UVA-URSI (L.) SPRENG FROM KORAB MOUNTAIN, WESTERN BALKAN.MACEDONIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING,40(1),69-74.
MLA	Stefkov, G.,et al."VARIABILITY OF THE ARBUTIN CONTENT IN WILD GROWING POPULATIONS OF ARCTOSTAPHYLOS UVA-URSI (L.) SPRENG FROM KORAB MOUNTAIN, WESTERN BALKAN".MACEDONIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING 40.1(2021):69-74.