Synthesis of silver nanoparticles via traditional Chinese medicine and evaluation of their antibacterial activities

doi:10.1039/d1ra05562c

	Synthesis of silver nanoparticles via traditional Chinese medicine and evaluation of their antibacterial activities
	Yang, Yi 1; Zhao, Tao 1; Zhang, Tao 2
刊名	RSC ADVANCES
	2021-09-14
卷号	11 期号:47 页码:29519-29526
DOI	10.1039/d1ra05562c
通讯作者	Zhao, Tao(zhaotao@shsid.org) ; Zhang, Tao(zhangtao@simm.ac.cn)
英文摘要	Silver nanoparticles (AgNPs) are widely used in antibacterial research, but diverse methods for the green synthesis of AgNPs are still underexplored. Phenols, the major components in traditional Chinese medicines (TCMs), can reduce silver ions (Ag+) to prepare AgNPs. The representative phenolic compounds are flavonoids and chlorogenic acid (CA) in TCMs. Herein, we report a new strategy to prepare AgNPs via decoctions and dregs of TCMs as reductants and dispersants. Lonicera japonica flos (LJ), Astragalus membranaceus (AM), and Eucommia ulmoides bark (EU) were chosen due to their high contents of phenols. H-1-NMR and HPLC were run to monitor the reaction for AgNP synthesis in decoctions, and XRD and TEM analyses were performed to characterize the synthesized TCMs-AgNPs. In addition, AgNPs prepared by spent Chinese medicinal grounds (SCMGs) were characterized by IR and XRD. The antibacterial assessment demonstrated that these TCMs-AgNPs significantly inhibited the growth of S. aureus and P. aeruginosa and effectively protected lettuce leaves against P. aeruginosa infection. Taken together, this study developed a new synthetic strategy that used decoctions and dregs of TCMs to obtain AgNPs with excellent antibacterial activity, which indicated the potential antibacterial application of these new TCM-based AgNP materials.
WOS关键词	LONICERA-JAPONICA ; CHLOROGENIC ACID
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000702237900036
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/297575]
专题	中国科学院上海药物研究所
通讯作者	Zhao, Tao; Zhang, Tao
作者单位	1.Shanghai High Sch Int Div, Shanghai 200231, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Yang, Yi,Zhao, Tao,Zhang, Tao. Synthesis of silver nanoparticles via traditional Chinese medicine and evaluation of their antibacterial activities[J]. RSC ADVANCES,2021,11(47):29519-29526.
APA	Yang, Yi,Zhao, Tao,&Zhang, Tao.(2021).Synthesis of silver nanoparticles via traditional Chinese medicine and evaluation of their antibacterial activities.RSC ADVANCES,11(47),29519-29526.
MLA	Yang, Yi,et al."Synthesis of silver nanoparticles via traditional Chinese medicine and evaluation of their antibacterial activities".RSC ADVANCES 11.47(2021):29519-29526.