A typical derivative and byproduct of tetrabromobisphenol A: Development of novel high-throughput immunoassays and systematic investigation of their distributions in Taizhou, an e-waste recycling area in eastern China

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	A typical derivative and byproduct of tetrabromobisphenol A: Development of novel high-throughput immunoassays and systematic investigation of their distributions in Taizhou, an e-waste recycling area in eastern China
	Zeng, Kun; Zhang, Zhen; Liu, Liyuan; Shao, Jie; Gu, Lantian; Liu, Huizi; Qu, Guangbo; Shi, Jianbo; Jiang, Gui-bin
刊名	ENVIRONMENTAL POLLUTION
	2020-08
卷号	263 页码:1-16
关键词	Immunoassay Tetrabromobisphenol A bis(2-hydroxyethyl) ether Tetrabromobisphenol A mono(hydroxyethyl) ether Monoclonal antibody Distribution
ISSN号	0269-7491
英文摘要	Environmental distribution and concentration of tetrabromobisphenol A bis- (2-hydroxyethyl) ether (TBBPA-DHEE) and tetrabromobisphenol A mono- (hydroxyethyl) ether (TBBPA-MHEE), are obscure due to the lack of available analytical methods. Here two novel immunoassays were established to systematically investigate their distributions in Taizhou, Eastern China. Five monoclonal antibodies against pollutants were generated with two designed haptens through animal immunization. After matched with different coating antigens/antibodies, ELISAs were established (LOD for TBBPA-DHEE, 0.12 ng/mL, based on OVA-M3/mAb-D4G6; LOD for TBBPA-MHEE, 0.79 ng/mL, based on OVA-M3/mAb-D2G6) and applied for investigation of their occurrences at a typical e-waste recycling area after 2-year samples collection, where the total 33 water, 32 soil and 16 biological samples were collected with the highest concentrations of 3.46 ng/mL, 2.76 ng/g (dry weight, dw) and 5.01 ng/g (dw), respectively. Meanwhile, our study also indicated that at the centralizing e-waste recycling sites the serious pollution for both chemicals still existed despite of various efforts. Besides, obvious improvements were observed at an abandoned e-waste recycling region treated and remedied for many years by the local Chinese government. These findings highlight the importance of policy decisions in treatment of pollutants to reduce organic pollutant-related health risks. (C) 2020 Elsevier Ltd. All rights reserved.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/44588]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Zeng, Kun,Zhang, Zhen,Liu, Liyuan,et al. A typical derivative and byproduct of tetrabromobisphenol A: Development of novel high-throughput immunoassays and systematic investigation of their distributions in Taizhou, an e-waste recycling area in eastern China[J]. ENVIRONMENTAL POLLUTION,2020,263:1-16.
APA	Zeng, Kun.,Zhang, Zhen.,Liu, Liyuan.,Shao, Jie.,Gu, Lantian.,...&Jiang, Gui-bin.(2020).A typical derivative and byproduct of tetrabromobisphenol A: Development of novel high-throughput immunoassays and systematic investigation of their distributions in Taizhou, an e-waste recycling area in eastern China.ENVIRONMENTAL POLLUTION,263,1-16.
MLA	Zeng, Kun,et al."A typical derivative and byproduct of tetrabromobisphenol A: Development of novel high-throughput immunoassays and systematic investigation of their distributions in Taizhou, an e-waste recycling area in eastern China".ENVIRONMENTAL POLLUTION 263(2020):1-16.