Breath Pentane as a Potential Biomarker for Survival in Hepatic Ischemia and Reperfusion Injury-A Pilot Study

	Breath Pentane as a Potential Biomarker for Survival in Hepatic Ischemia and Reperfusion Injury-A Pilot Study
	Wang, Changsong 1; Shi, Jinghui 2; Sun, Bo 1; Liu, Desheng 1; Li, Peng 1; Gong, Yulei 1; He, Ying 1; Liu, Shujuan 1; Xu, Guowang 3; Li, Jianyi 4
刊名	plos one
	2012-09-11
卷号	7 期号:9 页码:449401
通讯作者	许国旺
产权排序	3, 9
英文摘要	background: exhaled pentane, which is produced as a consequence of reactive oxygen species-mediated lipid peroxidation, is a marker of oxidative stress. propofol is widely used as a hypnotic agent in intensive care units and the operating room. moreover, this agent has been reported to inhibit lipid peroxidation by directly scavenging reactive oxygen species. in this study, using a porcine liver ischemia-reperfusion injury model, we have evaluated the hypothesis that high concentrations of breath pentane are related to adverse outcome and that propofol could reduce breath pentane and improve liver injury and outcome in swine in this situation.
学科主题	物理化学
WOS标题词	science & technology
类目[WOS]	multidisciplinary sciences
研究领域[WOS]	science & technology - other topics
关键词[WOS]	critically-ill patients ; mediated lipid-peroxidation ; oxidative stress ; diphenyl diselenide ; hydrogen-peroxide ; propofol ; liver ; rat ; cell ; expression
收录类别	SCI
语种	英语
WOS记录号	WOS:000308638700100
公开日期	2013-10-11
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/118210]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Harbin Med Univ, Affiliated Hosp 1, Dept Anesthesiol, Harbin, Peoples R China 2.Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Anesthesiol, Wuhan 430074, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian, Peoples R China 4.Third High Sch Harbin, Harbin, Peoples R China
推荐引用方式 GB/T 7714	Wang, Changsong,Shi, Jinghui,Sun, Bo,et al. Breath Pentane as a Potential Biomarker for Survival in Hepatic Ischemia and Reperfusion Injury-A Pilot Study[J]. plos one,2012,7(9):449401.
APA	Wang, Changsong.,Shi, Jinghui.,Sun, Bo.,Liu, Desheng.,Li, Peng.,...&Li, Enyou.(2012).Breath Pentane as a Potential Biomarker for Survival in Hepatic Ischemia and Reperfusion Injury-A Pilot Study.plos one,7(9),449401.
MLA	Wang, Changsong,et al."Breath Pentane as a Potential Biomarker for Survival in Hepatic Ischemia and Reperfusion Injury-A Pilot Study".plos one 7.9(2012):449401.